Villainous Breakdown/Examples

Star Wars

 * Prelate Verge: Suffers one after Chalis messes his ship.
 * Denetrius Vidian: He loses his cool almost any time Baron Danthe reports demands for unrealistic production increases. He has another when Captain Sloane tries to have him arrested for his treason against the Emperor.
 * Belkor Dray: He loses it when his and Cham's plans start coming undone in the end, going from crying to giggling to having a conversation with the corpse of the pilot he shot.

Harry Potter

 * Lord Voldemort: In Harry Potter and the Deathly Hallows, after hearing a goblin reporting him about Harry breaking into Gringotts and stole Helga Hufflepuff's Cup, which is one of the Horcruxes, Voldemort was absolutely angry and killed that goblin immediately. After that, it was some other unfortunate goblins, bank guards and Death Eaters turn. Voldemort mercilessly killed many of them with the Death Curse.
 * In the film adaptations, Voldemort went too far expressing this breakdown by slapping Lucius out of his logical reasoning about their situation, blasting Pius with a Killing Curse, and even had a brief physical fight against the revealed still-living Harry instead of both of them simply exchanges their trademark spells.
 * Dolores Umbridge: She expresses her breakdown further by restraining one of the angry centaurs that surrounds her and stated that she will have order on Hogwarts' grounds and beyond before being dragged away by them.
 * Unnamed Mountain Troll: Furiously makes an attempt to try to attack Harry Potter due to the latter shoving his wand in one of his nostrils. During the breakdown, he is naturally oblivious to other threats (namely Hermione and Ron near him) when Ron successfully knocks the troll out flat by taking his club away with a levitation spell and having it smack him in the head.

A Song of Ice and Fire

 * Gregor Clegane: As he fights Oberyn Martell, Gregor Clegane gets progressively more enraged. A combination of his exceptionally dim wits and the realization that he is being publicly accused of his crimes in front of the entire court leads to him screaming at Oberyn again and again. Finally, he MURDEROUSLY breaks down by yelling his early crime of savagely killing Elia Martell's whole family, before crushing Oberyn's head in sheer brute force. Even killing Oberyn doesn't help, because the spear that Oberyn wounded him with during the fight is coated in poison, leaving Clegane to die, slowly and painfully, and letting him screaming in agony and pain over the course of days.
 * Lysa Arryn: She sees her childhood crush forcibly kissing Sansa Stark, who is her niece, Lady Arryn goes completely insane, trying to throw poor Sansa (who did not instigate the kiss) out of the Moon Door. Her breakdown is cut short when she is thrown out said Door herself.

The Hunger Games

 * Cato: In the first novel, when Katniss destroys a stockpile of food and supplies belonging to the "Career" tributes that had given them a nigh-unbeatable edge, their leader, Cato, has a thrashing, screaming meltdown — Katniss, who manages to hide in the bushes just before he makes it back, marvels in a frightened way that people really can snap like that — and finally kills the engineer he'd had working for him, which obviously doesn't help his odds.

Divergent

 * Jeanine Matthews: In the first novel, Jeanine panics after her plans have failed & she furiously attacks Tris, only for the latter to hit her in the head, all this after Tris made Jeanine have a taste of her own medicine to undo her plans to commit genocide on Abnegation using Dauntless.

The Count of Monte Cristo

 * Fernand Mondego: He was angry when his son quit to duel the Count of Monte Cristo / Edmond Dantès and challenged Edmond Dantès to reveal himself. However, when the Count of Monte Cristo revealed himself to be Dantès, all of Fernand's rage had soon turned into sheer fear, and so horrified he was that he stumbled to his house, only to find out that his wife and son had abandoned him. Then, Fernand cried in despair and committed suicide.
 * Gérard de Villefort: Villefort's breakdown, or breakdowns, had several steps, one by one, and more and more intense.
 * First, when he knew about his second wife, Madame Héloïse de Villefort, had committed the serial poisoning of his first in-laws (the Marquis and Marquise de Saint-Méran, parents of his first wife, Renée de Villefort, née de Saint-Méran), servant and daughter, Valentine (he and Renée's child), Villefort can hardly hold composure. He coldly and outright declared himself as a judge in front of his second wife, and he harshly declared that she will be on court, ultimately driven her to suicide.
 * On the court against the murderer, Benedetto, Villefort was shocked to know the date of birth of the criminal which lead him to remember his affair with Baroness de Danglars which cause a child to born, exactly the same day and same place Benedetto was born. Villefort's composure was shaken once again when Benedetto revealed that he is the illegitimate child of Villefort, and he could hardly control himself from confessing his sins to everyone in Paris.
 * After returning home, scared and paranoid, Villefort only found that his wife dead with their son Édouard (he and Héloïse's child). He found his wife's last letter, which revealed that she was just a well-intentioned extremist who did everything for her son and had to kill him since she had choice no longer. This event even shocked Edmund Dantès, who had just revealed his true self to Villefort, yet never meant to harm his son. At last, all of those events above, and finally - Edmund Dantès's revelation, had crushed Villefort's mental state, turning him into a complete madman.
 * Héloïse de Villefort: She committed suicide and killed her son right after her husband accused her.

Others

 * Baroness Rodmilla de Ghent: She fainted and broke into crying after her affair with Villiefort was indirectly revealed by Benedetto.
 * Mulgarath: In the film, he discard his disguise and became angrier than ever after the death of his minions, chasing Jared in a blind rage.
 * Lord Capulet: Flies into a violent rage when his daughter Juliet politely refuses to marry Paris.

Star Wars

 * Wat Tambor: He goes through one when faced with the prospect of an inevitable Republic victory; his tactical droid TA-175 rats out Tambor's inefficiencies to Count Dooku behind his back and the droid agrees with Dooku's orders to evacuate Lessu against Tambor's wishes.
 * Count Dooku: Dooku briefly yet silently loses his composure right before Anakin chops off Dooku's head when the fallen Jedi realizes that his master Darth Sidious wants him dead. His Angry Birds incarnation does not suffer a breakdown, however. This also foreshadows how Anakin will lose his mind to the Dark Side.
 * Emperor Palpatine: When he seemingly lost to in a lightsaber combat, Darth Sidious replied to Mace Windu "No! No! NOOO!.......YOU WILL DIE!" and released a torrent of Force lightning at him, but the Master of the Order uses his ligntsaber to deflect the Hidden Sith Master's attack and redirect Sidious' lightning back to his face. Then in a fit of rage he called Mace in front of his newly-arrived future apprentice Anakin Skywalker a traitor. In addition he becomes enraged at  after he refuses with resolve to turn to the dark side by killing his apprentice Darth Vader after he defeated him in a lightsaber combat. Then he unleashes torrents of Force lightnings at him which unknowingly turns Vader back to the light side and make him turn on him, and he directed his torrents of Force lightnings at him before being thrown to the core of Death Star II to his death.
 * Darth Vader: Darth Vader suffers this after his rehabilitation that led him to become the infamous black-clad cyborg Sith that we recognize today, when he learned that his own fear ended up making his wife Padme's determination to live after giving birth to their children gone and dying during the childbirth. He shouts in agony, thus fell to the dark side further. Also, earlier during his duel against at Mustafar, Anakin is defeated and (without warning) screams "I HATE YOU!!!!!" at his former master. This can be considered a hyper-breakdown since by this point, Anakin's love for his former master was completely destroyed by his transformation.
 * Mas Amedda: Undergoes one post-Endor, as serving as the Emperor's top lackey and running the Empire for him was all he lived for. Amedda never once considered his boss could be killed, leaving him at a total loss at what to do without him and any authority on an ISB-run Coruscant. Sloane offering him the chance to have his old job as Grand Vizer once she secures her hold on the Empire pulls Amedda out of his breakdown.
 * Kylo Ren: Kylo Ren had a serious issue on this because he would furiously use his lightsaber to butcher everything around him everytime he suffer this, even scaring his stormtroopers when he calls for them. However, there are instance where his breakdowns are at their worst:
 * Upon denounced by Snoke as a failure and droven back to his duty, Ren angrily slammed his mask on the elevator into pieces, before quickly regaining his composure as soon as the elevator door opens. By this point, he realized that his master might only use him for his own ends and must rebuild the galaxy with his own way.
 * Lashing out on Luke in their final confrontation for his past mistakes, only to be dismayed that the legendary Jedi was not directly fighting him. (Luke was in fact projecting his consciousness toward Ren, creating a hologram, in a sense.)
 * Snoke: As Snoke unveiled his true, darker personality when chiding Ren in The Last Jedi, it became apparent that he suffered this, barely able to contain his rage following his underlings' loss against The Resistance and Rey and co., so much that when goading Ren, he had unknowingly (or rather, foolishly) created a monster that surpassed him in Ren before it's too late.

Jurassic Park
Speed
 * Indominus Rex: Shocked to see that Owen's raptors, namely Blue, Echo, and Delta whom she recruited to her side turned against her, she ultimately snapped and incapacitated Blue. She proceeded to brutally kill Echo and Delta before doing the same with Owen, Claire, and Mitchell brothers. When she had a chance to kill the humans however, Rexy appears with Claire, who proceeded to maul her to the Jurassic World Lagoon with help of recovered Blue, allowing Mosy to kill her and avenge deaths that she caused.
 * Howard Payne: When he finds that the money bag contains a dye bomb towards the climax, he goes berserk and empties his entire weapon into the train roof, and then proceeds to fight with Jack Traven on top of the vehicle, which hilariously ends with him being beheaded while trying to boast that he is 'smarter' than the cop.

Transformers

 * Harold Attinger: Attinger completely loses himself when his right hand Savoy fell off the building after pursuing Cade (which is worsened by the fact that his pawn, Joshua Joyce, turned against him by the time Galvatron permanently broke free from KSI's control). He then personally confronts Cade while the latter aids Optimus fight Lockdown by pointing a gun on him. Attinger then claims that there is no such thing as good or bad aliens & it's just the humans or the aliens. Right before he had a chance to kill Cade (as declaration for him as traitor of his own race), he was shot by the Autobot leader in the chest, thus avenging the deaths of Autobots (& presumingly humans) that he had killed on his genocide, also making him a true Decepticon.
 * Lockdown: After Autobots hijacked one of his smaller ships that later revealed contained Dinobots, he began to suffer this. He expresses the said breakdown by using the giant magnet on Autobots and Dinobots, until Optimus blasted the magnet several times until it was heavily damaged.
 * James Savoy: Ultimately snapped by Cade's choice to save Autobots (specifically Optimus Prime), he reveals his knife, giving warning that he will attempt to kill him in blind fury (presumed to be in similar manner with Shen's own attempt to kill Po during his breakdown). Cade however, prevent this from happening by pushing him to fall to his death, avenging death of Cybertronians (and presumably humans) that he killed also making him a true Decepticon.
 * Starscream: Perhaps the most painful and hilarious breakdown uttered by Starscream, as when he gleefully tries to kill Sam, turned into a painful and humiliating scenario when Sam retaliates with fired a grappling hook on one of his eyes, resulting Starscream screaming in agony and rage. Things became worse (or rather became more awkward, if not comical) when Lennox and his men interfere where Sam, still stuck with his hook, swung ankwardly due to Starscream's own angry tantrum like a madman. His breakdown eventually stopped when Sam ultimately impaled a bomb on his remaining optics, which explodes and tears his head into pieces while humans around him managed to move safety.

Chronicle

 * Richard Detmer: Unable to cope with the death of his wife, Richard ultimately consumed by uncontrollable rage and stromed the hospital, upsetly informs the unconscious Andrew that his mother has died and he angrily blames him for what has happened. This however, caused him to nearly kill himself as when Andrew awakened before attacking him in blind fury, he was sent to flying and fell to his death by Andrew himself until he was saved by Matt who intervenes.
 * Andrew Detmer: Angered when Matt saves his abusive father, he and Matt have a violent showdown in the middle of downtown Seattle, with Matt pleading for Andrew to stop, and Andrew refusing, screaming that Matt was never there for him. He proceeds to outright declare himself an "apex predator", and hits Matt with a bus. The brutal confrontation became worse as police ultimately interferes by open fires on Andrew, only to the bullets stopped in the mid air by Andrew's powers. Andrew then proceeds by mindlessly destroy everything around him, breaking all the windows of the buildings surrounding him. Realizing that Andrew can't be stopped or reasoned with, Matt reluctantly killed him, putting an end of his suffering and destruction that he caused.

Marvel Cinematic Universe

 * Winter Soldier: When Captain America reveals both his and his own true identities to Winter Soldier and he revealed that they originally friends, Winter Soldier suffers this out of conflict within his psyche between his brainwashed self and the good inside him that awakened by Captain America earlier, effectively breaking most of HYDRA's programming in his mind and allow him to redeem himself.
 * Ultron: Shocked to see that an Avenger has turned his latest constructed a new robotic body into a new Avenger named Vision who immediately stripped him from the internet upon their confrontation, he angrily tossed the weakened Vision and accelerate his evil plans. Though he still retains some of his composures, he was obviously became more bitter than ever, and even unable to comprehend why although both he and Vision already see the negative traits of humanity, Vision still believed that the good inside humanity still exist.
 * Thanos: After being reminded of Gamora’s death at his hands, Thanos uses the Infinity Gauntlet to shatter a moon and throws it at Iron Man, Spider-Man, Drax, Star-Lord, Mantis, Doctor Strange and Nebula, all while wearing an expression of absolute fury.
 * He goes through a more understated breakdown in the climax of Avengers: Endgame. After spending two movies as a calm and collected overlord insistent that everything he does is for the greater good of the universe, he time-travels from 2014 to 2023 and finds out that, though he did achieve his goal, everyone hates him and they're actively trying to undo his "great work". Dropping the delusions, he first announces he intends to completely destroy the universe and make it anew just so, that way, there will be no one left to remember the old one, and the new universe will believe that he was in the right all along.

Batman Returns

 * Catwoman: Wrecks her own apartment after nearly killed by Max and suffer seizure from the injuries that affected her sanity.
 * Penguin: The Penguin goes through a breakdown when he discovers that the children were saved by Batman. He immediately screams in a blind fury and declares that the time has come to "punish all of God's children".

Others

 * Simon Doonan: When Aase Ludvigsen recognizes him as a man who raped her and tries to attack him, he angrily throws her into the ocean and then tries to hold all lifeboat passengers hostage at gunpoint, only to be killed by Fifth Officer Harold Lowe, who, in order to save others, hits him powerfully in the head with the paddle and snaps his neck.
 * Cal Hockley: After watching his fiance Rose reunite with Jack Dawson on the Grand Staircase, Cal is watching their emotional reunion, upset. His valet, Lovejoy, leads Cal away, accepting that they cannot seperate Jack and Rose. Cal refuses to accept defeat. He grabs Lovejoy's pistol, and attempts to kill Jack, chasing Jack and Rose down the Grand Staircase, much to the horror of the other passengers.
 * Biff Tannen: In Back to the Future Part II, when Marty McFly attempts to steal back the sports almanac from Biff, he drives his car in circles, in an attempt to get Marty off his car (and to possibly kill him). After Marty snatches back the book, Biff revs up his car, and accelerates the vehicle, to run down Marty in a tunnel.
 * Will Teasle: after one of the national guardsmen destroys Rambo's hideout with a rocket launcher, Teasle throws an intense fit in anger out of losing his chance at vengeance against Rambo for presumably killing Art Galt.
 * Adolf Hitler: In virtually the whole of Downfall. In the week leading up to his death, Hitler has a lot of breakdowns.
 * When he learns that Himmler, his most trusted underling, has betrayed him to the Allies by offering to negotiate a peace settlement... and before that, when Herman Goering says that if he doesn't get a reply by 2200 hours (10 pm), he'll assume that Hitler incapacitated and take over.
 * When he's told that one of his generals could not muster up enough forces to halt the Allied offensive on Berlin, Hitler quietly and calmly orders everyone except his top people out of the room, and then completely loses his mind, ranting and raving so loudly they can hear him outside a steel door.
 * In Fargo, as his plans (which were not that incredibly well thought out to begin with) spiral rapidly out of control, Jerry Lundegaard experiences several relatively minor outbursts of increasing intensity as things he did not anticipate come back to bite him (such as an arm-waving tantrum in a frozen carpark while trying to scratch ice from his windscreen, and slamming his blotter down on his desk). By the end of the movie, everything has gone catastrophically wrong and he's been forced to flee, and when the police finally catch up with him he's reduced to a hysterical, shrieking wreck of a man writhing about on the bed of a motel room as the cops try and restrain him. All of this just serves to show what an ultimately pathetic, inadequate man Jerry is and how deeply out of his depth he's gotten himself.
 * In The Matrix, when Neo comes back from the dead, Agent Smith loses what composure he still had and charges at him in a fury. All of this is overshadowed by his scenery-chewing, spit-spraying breakdown at the end of Revolutions. When he sees that Neo will not stay down no matter how many skyscrapers he gets smashed through, he goes on a minute-plus rant about the pointlessness of existence.
 * Thunder (Big Trouble in Little China): Horrified at Lo-Pan, his master killed by the heroes, he ultimately screams "NO!", causing his own power to making his body inflates like a balloon before exploding. This forces the heroes to taking cover before they get caught within the blast.
 * Dreyfus: While his actions before killing himself within the explosion that he ironically started may not counted as one, it's obvious that he has lost his composure over the chaos that the genocidal Koba caused. He even furious when Malcolm tries to reason with him, implies that he never agreed with him to give the apes for live coexist with remnants of mankind.
 * Harry Wormwood: He has two meltdowns in Matilda. After tearing up Moby Dick, he claims to be fed up with Matilda's reading (even though she needs it) and wants her to act more like she is part of the family. Later, in response to Matilda's taunts to yell at her, Harry goes into a fit of rage and sets out to give Matilda a beating, but not until she slams her door into his face with her new-found psychic powers.
 * In Pirates of the Caribbean: At World's End, after HMS Endeavour was attacked by both Black Pearl and Flying Dutchman, Lord Cutler Beckett showed us a VERY RARE example of a absolutely CALM breakdown. Instead of giving the orders of abandoning the ship, Beckett only spoke "It's just... good business." and then he awaited on the sinking ship until it blew up, killing him.
 * General Thade: Realizing that the human protagonist Leo sealed him within a prison within the shipwreck and his general turned against him, Thade eventually snapped and firing his laser gun in blind fury on the cell's impenetrable door, only to stopped later and cowering, finally realized that he is lost.
 * Super Shredder: After getting blasted to the docks by the Turtles, Shredder drank the last canister of mutagen to become Super Shredder. In a rage, he started destroying the docks to kill the Turtles. Despite Leonardo's pleas to stop, Super Shredder said "Then so be it!" and continued bringing the docks down as he didn't care that it will kill him too. Realizing that they are turtles, the Teenage Mutant Ninja Turtles jumped into the river with their limbs and head retracted inside their shells before Super Shredder brought the docks down, crushing him.
 * King Stefan (Maleficent): When Maleficent regained her stolen wings, he lost his composure to the point that he became suicidal, where he desperatedly and angrily shot her with a crossbow so his men can shot her. But this effort was vain when Maleficent flew her into a nearby tower, where instead killing him, she spared him. This however, made Stefan had an opportunity to killed her by stabbing her from the back, though the latter's resistance made him fall to his death.
 * Marty Wolf: In Big Fat Liar, Marty Wolf goes through a breakdown when he looks into the mirror and discovers that he turned blue by Jason and Kaylee. He screamed "OH MY GOD!!!!!!!!" out loud in horror.
 * Grimm Jim: After Bulletproof Jackson wins a game of poker against him, Grimm yells "You SON OF A - !" and pulls out his gun, then shoots Old Drunk George in the shoulder before kidnapping Ashley.
 * Edwin Epps: Attacks Solomon Northup with a knife and orders him to stay away from Patsey, but he crosses the line when he snatches a whip and lashes her savagely.
 * Captain Vidal: After being drugged by Ofelia whom attempted to taking her little brother away, Vidal takes out his rage on her before he receives his comeuppance: He snatches the baby from her and shoots her in the chest, only for the baby himself secured away by Mercedez and she had her fellow rebel shot him in the chest avenging Ofelia and innocent farmers that he brutally killed due to mistaken as disguised rebel soldier.
 * Cruella De Vil: In 102 Dalmatians, after a brief reunion with one of the dalmations that she used to kidnapped as puppy, she hears the chimes of Big Ben that triggers the hallucination where she seeing black spots everywhere. This resulting her reverts back to her original obsession with spots.
 * Koba: Has foreshadowed to suffer this when all the apes learned his true nature and starting to became disloyal to him (due to him killed Ash whom feels that purging human race was the bad idea), he resorts to blackmail them and having those whom still loyal to Caesar to incarcerated and left to rot. The breakdown eventually began when as result of being psychologically overpowered by Caesar whom revealed alive and their fight were cut short by explosion that started by Dreyfus, he uses this opportunity to kill all presenting ape by a gun started from Caesar himself. Blue Eyes' attempt to stop him even made everything worse as Koba shoots Maurice in retaliation whilst screaming like the mad man, forcing Caesar to tackle him and later, send him fall to his death after hypocritically states "Ape do not kill ape."
 * Smaug: Suffers this after being tricked into the Dwarves' trap in form of a giant statue that drowned him into the river of gold, where he broke free from the molten gold and flew toward the Lake-town to devastate it in retaliation of their assistance on Dwarves. It should be noted that when he correctly guessed that the Lake-town citizens assisting the Dwarves to killed him and decided to go for burn them all, he still retaining his composures until Dwarves' trap for him ruined it completely.
 * The Grinch: In the Live-Action movie, he was a young child at school who tries to be with young Martha May, but he is being bullied by the young Mayor and the other kids twice. He then had enough of their bullying. The Young Grinch gets angry and destroys young Martha May's gift and the Christmas tree.
 * The Garthok: Attacks Beldar Conehead in a fit of rage.
 * Mola Ram: He began taking more agressive attempts to retrieve his sacred stones from Indiana Jones in spite the major loss of his minions, only for the hero called for Shiva to caused the stones's power rejected the evil cleric's clutches by burns his hands, caused the excruciating pain that so painful which caused him to fell onto the river and devoured by crocodiles.
 * Tony Montana: Suffers multiple villainous breakdowns in Scarface. His first breakdown occurred when he was assigned by Alejandro Sosa to assassinate an activist via an explosive device. Despite the fact that the activist's wife and children are inside of the target's vehicle, Alberto (also employed by Sosa) tells Tony to follow the vehicle to the UN building anyway. Tony expresses his anger with Alberto that he is crossing his line of allowing children to be killed in the name of profit for his organization. He also mocks Alberto as if he feels like a big man for killing children. When the activist finally reaches the UN building, Tony kills Alberto before he can blow up the activist and his family. Enraged, Tony tells the corpse of Alberto that he is not a worm like him and because he did not relent, he has now ended up dead. Tony also suffers a breakdown in the final scene of the movie. Under the influence of cocaine and enraged at Sosa for killing his sister Gina, he goes on a cocaine induced rampage in his own mansion, killing hundreds of Sosa's men. When he is finally cornered, he demands Sosa's men to put him down. He repeatedly dares them to shoot him as he can take their bullets. He continually demands Sosa's men to kill him until The Skull (Sosa's top assassin) shoots him in the back with a shotgun, dead as his corpse falls to the water below.
 * Chucky: In Child's Play 2, when his soul transfer ritual failed at the Good Guy factory, Chucky blames Andy Barclay for him being stuck inside the Good Guy Doll for a long time and threatened to kill him, before pummeled by a bunch of Good Guy boxes pushed by Andy's foster sister Kyle just in time to allow Andy to get away.
 * Howard Payne: After the dye bomb explodes in his money bag, he sprays his submachine gun wildly in an attempt to kill Jack Traven.
 * The Dragon: When it is dumped with molten iron, it leaps from the vat and pursues Ellen Ripley, who it had spared until that point, but is showered with freezing water and blows apart from thermal shock.
 * The Riddler: After getting defeated by Batman and placed in Arkham Asylum, he becomes an insane lunatic and believes that he's Batman.
 * Poison Ivy: Wrecks her lab and sets it aflame.
 * Bane (Dark Knight Rises): When Batman figures out the secret to his immense strength, he starts damaging his opponent's mask, making him attack with increased power, but also with less coordination until the Caped Crusader gains the upper hand.
 * Regina George: After realizing Cady Heron tricked her into eating Kalteen bars, she throws a huge tantrum and then starts writing horrible words in her burn book.
 * Carrie White: After being dumped with pigs blood she then decides to lock the student's and teachers in the gym and starts to move objects with her mind causing a chaos at the prom, then electrocute's Mr Frommn (English Teacher) causing him to catch on fire as well as the building buring all the remaining students inside the inferno prom.
 * Christine: When Leigh is at Darnells garage Christine is hiding in a pile of scrap and tries to run her over but Leigh just escapes Christine as she rams into an old car and uses it to attack Dennis and Leigh. She then rams into Darnell's office casuing Arnie to fly out of her window killing him with a sharp piece of glass stabbed in him. Christine the exacts revenge on both Dennis and Leigh tries to run them over.
 * Shere Khan: Becomes furious when Baloo, Bagheera and the wolves side up with Mowgli and vows to kill them before fighting them all in order and defeating them so he can pursue his opponent Mowgli as the Man Cub sets a trap to lure him in.
 * Norman Osborn: After getting fired by the directors of Oscorp, Norman screams at the directors, saying how much he sacrificed.
 * King Ghidorah: Has a minor one when Godzilla traps him underwater, and is visibly panicking when Godzilla bites off one of his heads and struggles to break free. The real one comes when Godzilla enters a newly-empowered state due to Mothra transferring her energy to him in her final moments. Within seconds, Ghidorah goes from the arrogant, sadistic tyrant to frantically crawling away, hissing and shrieking in pure terror as Godzilla powers through all his attacks, incinerates his entire body, and then eats his remaining head.

DC

 * Lex Luthor: Always spectacular when it happens.
 * Darkseid: When Batman forced Darkseid to release Supergirl by threating to blow up Apokolips (and proving Darkseid that he wasn't bluffing) Darkseid didn't take it very well. He vented his frustration by beating the crap out of Batman (who only survived thanks to a Mother Box) before giving into Batman's terms.
 * Darkseid had an ever bigger one during the Our Worlds At War event after Wonder Woman and Raven resorted his powers, and did it in such a way that a bit of Wonder Woman's inherent love and compassion found its way into Darkseid's soul. Darkseid could only howl in impotent fury when he realized that Wonder Woman had hurt him in the worst way possible.
 * Brainiac: He's prone to doing this when he loses control of a situation.

Marvel

 * Norman Osborn: His veneer of civility can only withstand so much, for so long.
 * Red Skull: When he was locked up in a shelter by Magneto.
 * Thanos: Had several during The Thanos Imperative, mostly because he was unwillingly resurrected and afterwards confronted with a whole eldritch abomination-like universe filled to the brim with what he hates the most: Life.
 * Carnage: Deadpool's taunts and jeers about Cletus being a cosmic plaything, coupled with various contrived coincidences that have occurred, cause Carnage to try and force the patients and staff of a mental institution to answer his nonsensical questions about being "controlled" by higher powers as he rants about breaking into one nuthouse after another until he gets satisfactory answers. After Deadpool tricks him against doing through him into mangling Shriek - something he thinks the "higher powers" tried to warn him against doing through the muttering of a few patients.
 * Doctor Octopus: While a copy of his consciousness took control of the Living Brain, Doctor Octopus went on a destructive rampage after discovering his original self had admitted that Peter Parker made a better Spider-Man than he did.

Sonic the Hedgehog (Archie Comics)

 * Dr. Eggman: After Sonic the Hedgehog defeats Dr. Eggman in what was supposed to be their final battle, Eggman completely loses his sanity and screams in insane fury. Then starts babbling incoherent words before tearing off pieces of his own moustache, taking a swing at Sonic and falling to the ground sobbing, much to Sonic's horror.

Total Drama

 * Heather: After her hair is shaved and she gets eliminated from the competition for that, Heather screams loudly.
 * Blaineley: Blaineley gets mad when she failed to make Bridgette and Geoff fight in the first Aftermath of Total Drama World Tour.
 * Courtney: She goes insane after her breakup with Duncan.
 * Alejandro: During the final challenge, Alejandro's mind slips at the name of his brother, José, because he envy his brother on how he bests him at everything, even calling him Al, to which he hates because he knows, provokes him.
 * Dave: He goes out of control after Chris replays Sky's audition tape and has a boyfriend back home.
 * Jacques and Josee: Their obsession with winning, combined with coming in second or third, sets them off, but Josee loses her temper more because of her temper tantrums. The breaking point is when they were eliminated when they came in last by the Police Cadets, Don was suspicious on how they were taking their loss well until Josee throws another temper tantrum, when she was about to throw a hot dog car, but Jacques told her it was over leading her to cry and making the cart fall on them.

Avatar: The Last Airbender/The Legend of Korra

 * Azula: Began to losing her sanity started from her inability to cope with her friends (namely Mai and Ty Lee)' decision to let Zuko away out of Mai's love with him along Ty Lee's agreement with that. This worsen by the fact where her father Ozai thought that she should be in charge as the King of Fire Nation instead of go with him in their crusade once Sozin Comet passed the earth but doubts that the said position suit for her. In the end, her fractured sanity eventually made her incarcerated in mental institute.
 * This breakdown was already predicted by Iroh and Zuko when they reunited, whom believe that her breakdown can give him advantages. But this horribly backfires as she was turned out more dangerous when her sanity slipped away where she attempted to kill Katara whom observing the fight, forcing him to save the waterbender with the ill-advised action (using his body as a shield instead redirect the lightning blast like what Iroh taught him previously). This ultimately led Katara, whom originally told to watch the whole fight to interfere and incapacitate Azula herself instead. With her defeat, she completely suffered a mental breakdown. This was caused by her insecurity on the thought of her mother loving Zuko more than her.
 * Zuko's harsh life mostly became the reasons why the fire prince suffers his own breakdowns, in which he releases this during the thunderstorm where his original motivation was tries to learn lightning redirection. His exile at hands of Ozai greatly disturbed him, though when he chooses to redeem himself, he finally regained his lost composures. When he finally became the Firelord, he also suffer the breakdown which turned out caused by his own fear to became as evil as his evil father was.
 * Hiroshi Sato: He attacks his own daughter Asami who aids benders out of his inablility to cope with both her said decision and reality where there are still good benders that exist alongside the evil ones, as he indiscriminately despise benders as one of them killed his wife. This doubles as Moral Event Horizon.

DC Animated Universe

 * Joker (DC Animated Universe): In Return of the Joker, he yelled at Terry, whom became the second Batman, as he was less entertained with his jokes and was different with his predecessor Bruce Wayne.
 * Bane (Batman: The Animated Series):

Teenage Mutant Ninja Turtles (2012)

 * Bebop and Rocksteady: Suffered this after the Foot Ninjas poured mutagen on them, turned them into a rhinoceros and warthog, respectively.
 * Slash: After Raphael calls him pure evil, Slash grew enraged and attempts to kill him.

The Simpsons

 * Sideshow Bob: In The Italian Bob, he swears a vendetta on Simpson family for accusing him.
 * Frank Grimes: After Homer Simpson was applauded by his coworkers for winning a contest meant for children, Frank Grimes vents his frustration in a brief moment of madness, until he decides to grab high voltage wires without wearing safety gloves.

South Park

 * Eric Cartman: When Scott Tennerman burns Cartman's $16 in front of them and still Cartman as pathetically annoying, Cartman shouts Scott Tennerman's name in rage and swore revenge on him for ridiculing him a bunch of times.
 * Randy Marsh: In A Nightmare on Face Time, nobody come to his old Blockbuster, he begins to deteriorate then wandering the store menacingly, stalking Stan.

SpongeBob SquarePants

 * Plankton: Flies into a blind rage and screams at the top of his lungs when his plans fail or when things go wrong.
 * Mr. Krabs: In the episode Squeaky Boots, He took SpongeBob's boots away from him, because of the squeaky noise getting on his nerves. The squeaky noise hallucination are forcing him to tell the truth (similar to the Narrator of "The Tell-Tale Heart"). Mr. Krabs then turns insane and started eating the boots. At the end of the episode, though eventually regained his composures after eating the boots, he got hiccups sounding exactly like the squeaky noise of the boots, much to his dismay.
 * This however, the first cases of his breakdowns, as his descent into madness with money by the event of Post-Movie Seasons, the chance of him suffer another Villainous Breakdown are skyrocketing, though fortunately mostly in form of pathetic tantrum. One of the instance was when Pearl confiscated a special money that given to Mr. Krabs for saving money-production factori in retribution of ruined her own holiday, resulting him crying to the point where his tears floods the entire place like tsunami.
 * Mrs. Puff: After years of putting up with SpongeBob's wreckless driving, she was finally driven insane in Demolition Doofus, when she apparently lost her ability to puff, thanks to SpongeBob. She later gets SpongeBob into a Demolition Derby in hopes of him getting killed by offering him "extra credit". As his bad driving makes him a star, Mrs. Puff snaps and tries to run over SpongeBob by using a huge monster truck (knocking over innocent bystanders in the process). Instead, she destroys her boating school, but she turned back to normal and regained her sanity, only with disappointment. The breakdown also doubles as Moral Event Horizon.

My Little Pony

 * Queen Chrysalis: In episode "A Canterlot Wedding," the seconds before Chrysalis could marry Shining Armor, disguising herself as princess Cadence, Twilight Sparkle and real princess Cadence interupted the wedding. In rage, Chrysalis reveales her real changeling self and powered by Shining Armor's love even could defeat princess Celestia, and force her army to catch the Mane Six. Hovewer, it made her careless about the prisoners, so princess Cadence and Shining Armor could cast a special spell that threw the queen far away.
 * Sunset Shimmer: When Twilight tells her that the Equestria will do well without her, she seems to have given up. Unfortunately, the Human Mane Six's praise for her soon turns grew Sunset furiously and she pounces on Twilight.
 * Tirek (My Little Pony: Friendship is Magic): In the episode "Twilight's Kingdom - Part 2", Tirek is shocked that the Mane Six have magic again and finds himself completely overpowered by them.
 * Gilda: She snaps after being pranked by Pinkie Pie's plan.

Ren & Stimpy

 * Jerry the Bellybutton Elf: Eventually, he calls Stimpy to make him dinner which is lint loaf, he declares that he hates lint loaf. He then goes insane and tries to kill Stimpy. Eventually, he corners him and Stimpy says that maybe Jerry is cranky because he missed his dinner and that he could heat the lint loaf up in the microwave. When Jerry hears this, it makes him even more mad, he rips off his skin and reveals his true identity as a giant pork chop monster named Contorno and declares that he will eat Stimpy.
 * Ren Höek: He has two infamous breakdowns in two Ren & Stimpy episodes "Sven Hoek" and "Stimpy's Fan Club".

Transformers (Generation 1)

 * Lord Chumley: He loses it when his target Optimus has reached his control room, which even frightened Chumley's butler to hide in a tank. He immediately ask help from his Decepticon prisoners Blitzwing & Astrotrain to help him defeat Optimus, only to be tricked by the two into escaping & abandoned to meet his punishment at the hands of the Autobot leader.
 * Devastator: Due to the Autobots' attempting to control him & Megatron trying to counter their control, this causes Devastator's circuit logics to get fried, causing him to go berserk & attack both sides regardless of faction, even managing to destroy a space brigde intendend to be used by the Decepticons as a form of escape. He was soon calmed with the conjoined forces of the two.

Others

 * Magica De Spell: Went into a fist-shaking, near-bawling rage when Donald accidentally breaks her staff.
 * Prince Aragon: Angered when his future wife is being "kidnapped," and hatefully toward his sister, Aragon turns into his dark dragon form (similar in appearance to the dragon form of Maleficent from Disney's Sleeping Beauty) and fights Danny while burning the castle and the trees.
 * Vlad Plasmius: In Kindred Spirits, upon Danny's perfect clone's destruction, Vlad looks to Danielle/Dani with pure rage.
 * Patrick Bateman: In American Psycho, Bateman, envious of Allens' situation, brutally strikes Paul Allens with an axe, then dismember his dead body, while furiously shouting at him.
 * Loki Laufeyson: Makes attempts to attack the Avengers.
 * Glenn Quagmire: In "Quagmire's Dad", he physically assaulted Brian for unintentionally sleeping with his sex-changed father.
 * Lois Grffin: after Peter inadvertently gives away all the Christmas gifts and their turkey was ruined Lois tries to make good of the situation until Meg reveals they have no more paper towels which sends Lois into an insane rage for all her work being ruined.
 * Jasper: After her ship crash-landed by Steven and his friends, she forces Lapis to fuse with her into Malachite, only to backfires as Lapis turned out intended to having them sealed inside the ocean for good. When she appeared in Steven's consciousness in the Malachite Realm, her breakdown continued at the time when she tried to attack him in rage, but is prevented by Lapis from doing so and dragged into the water with her. This is especially seen when he becomes a Corrupted Gem Monster, as she becomes too angry and ferocious for Steven to help her.
 * Mojo Jojo: Mojo Jojo's eyes turns red and then the villain begins lashing out in a primal ape-like rage within his jail cell over his numerous times at the hands of the Powerpuff Girls.
 * Belladonna (All Dogs Go to Heaven): Flying into a homicidal rage is her normal manner of dealing with her plan falling through.
 * Lord Dominator: In the final episode of "Yonder Over Wander", she angrly rejects Wander.
 * Lord Boxman: In "We're Captured", Boxman snaps at Radicles, Enid and K.O. after they disrupt his dinner party with Professor Venomous and attacks them with a makeshift pie shooter made from Darrell and Shannon. In "Stop Attacking the Plaza", he loudly denies having an obsession of constant attacks on Lakewood Plaza Turbo to his "family" of robots.
 * Black Hat: He does this whenever he is displeased with the failures of other Cartoon Network villains, especially in cases like Boxman.
 * Dr. Flug: Roughly similar to his superior Black Hat to an extent, especially in cases involving that stupid villainess Dementia.
 * Li'l Gideon: In the episode "Little Dipper", as Gideon is interrogating Dipper, Dipper blows an air horn at Gideon's ear, causing Gideon to go on a furious breakdown and nearly crush Dipper with his fist, but he decides to spare him since Dipper could be useful to Gideon's evil plot. He goes on another breakdown during the climax of the episode as he is furiously smashing the mirrors with the shrinking flashlight to get to Grunkle Stan. In the season finale, "Gideon Rises," he is shown being very furious when he is arrested by the resident police when Grunkle Stan spilled the beans on him being a fraud. He then angrily calls for vengeance as he's being taken to jail.
 * Bill Cipher: In the episode "Dreamscaperers", he had his villainous breakdown after Gideon Gleeful called off the deal. He turns red and traps Mabel, Soos and two of Mabel's imaginary friends on the top of a giant angry Stan head and makes their nightmares to come true. Also, in the episode "Weirdmageddon 3: Take Back The Falls", after realizing he had been trapped in Stan's mind, Bill had his villainous breakdown when he changes forms while saying backwards to Stan that he may return before being destroyed by the latter.
 * Almighty Tallests: They have one in the unfinished episode "The Trial". In it, their plan to have Zim get deactivated during his Existence Evaluation is turmoiled once The Brains overload due to Zim's bad data, and proclaim him the greatest Invader ever. They are reduced into a crying fit once The Brains allow Zim to fly the Massive for 10 minutes.
 * Bradley Buzzcut: He is notorious for this. Buzzcut is shown to be extremely angry towards Beavis and Butt-Head. One time, he encouraged his students to beat up a special needs student. When Beavis and Butt-Head don't listen to his commands, he gets really enraged and yells out. Sometimes, his whole body turns red with bloodshot eyes. One time, he even violently punched Beavis and Butt-Head. He even spews out death threats towards his students.

Animated Film

 * Steele: After getting his team hopelessly lost in a blizzard, Steele can only sit and pout. When Balto arrives to the rescue, Steele, instead of being grateful, goes completely insane and goes completely out of his mind, trying to kill him, all the while looking completely psychotic. Then he deliberately sabotages Balto's trail (clearly not caring for the sick children who desperately need the medicine). When Steele gets back to Nome and tries to lie to everyone, only Jenna, the one female he wants straight through his lies and calls him out on it. When Balto returns it really kicks in. Steele instantly gets a mass Death Glare from every dog in Nome, Dixie, Steele's biggest fan dog slaps him in the face. And all the dogs leave and slam the boilers door in the contemptible malamute's face. Steele is therefore reduced to as a hated outcast by all those who'd looked up to him.
 * Nigel: One of the few cases where this actually happens in the first movie and leads into the second: villainous cockatoo Nigel loses his feathers in Rio and ends up suffering all sorts of humiliation as well as not being able to fly again. The minute he sees Blu and Jewel again in Rio 2, he snaps (complete with a flashback) and spends the entire movie going to all sorts of lengths to hunt them down.
 * Captain Gutt: After Manny steals his ship, Gutt is so furious, it's quite obvious that he's lost a huge amount of his sanity. He later beats Manny and the gang to the continent and takes Ellie & Peaches hostage, stating that Manny took everything he had from him, and the evil ape intended to do the same. Later during the battle when Precious the whale vanquishes his crew, only Gutt dodges them, now not caring about his crew. Then he attempts to kill Ellie but not before Peaches kicks him to the wall. Finally losing what's left of his sanity, Gutt then blocks Manny's path to return to his family, just as a landmass sends both of them hundreds of feet high.
 * The Beldam: As Coraline escapes from her, the Beldam attacks our heroine, attempting to pull her back into the Other World.
 * Aggie Prenderghast: Attacks Norman while refusing to listen to him about truth behind her legend and vowing revenge on Blithe Hollow for the way they treated her. During this breakdown, she couldn't think straight as she had problem in revealing her motives, which Norman mentioned instead, and her breakdown eventually ended with her gained composure and realized that there are some people that still cared with her.
 * Archibald Snatcher: After Lord Portley-Rind refuses to give him the White Hat, Snatcher wreaks havoc on the town, then attempts to kill Eggs by striking him with a wrench. But his most common breakdowns in the film involve when he gobbles up cheese and swells to a massive size, attacking his henchmen in a blind rage and seizing Winnie to force her father to give him the White Hat.
 * Fabrication Machine: Implied to suffer this as result of being abused by the Chancellor by forcing it making more machines beyond it's limit, and in response, having all of it's creations purges mankind and Chancellor himself.
 * Krudsky: He yells at Shaggy and Scooby for ruining his show and his rage lets loose when he tries to crush Fairy Princess Willow with his flyswatter. In the climax, he makes an attempt to destroy our heroes.
 * Black Samurai: He goes so far as to attack Shaggy and Scooby in the final battle, as both of them turned out has mastered the swordmanship skills that made them enough to be his formidable opponent.
 * Darla Dimple: When making attempts to sabotage the animals' performances, Darla snaps and pulls many switches. After she fails, she yells at Danny and ends up revealing her true intentions.
 * Baron Ruber: In the beginning, out of his madness and power hunger, he attacks King Arthur's knights, killing Sir Lionel and attempting to do the same to King Arthur. In the climax, he attacks Kayley in a blind rage for being an obstacle in his way.
 * Jenner: Attacks Mrs. Brisby to steal the stone and attempts to slash Justin with his sword.
 * Drake: Attacks Hubie in a blind rage.
 * Lord Business: He briefly suffers this when he upon learned that Bad Cop's good side named Good Cop in his mind hinder him to be a better underling (especially when the Bad Cop is not ruthless enough to freeze his parents with Kragle), so he solved this by erasing the Good Cop face in Bad Cop's head, rendering the good side dormant.
 * Bad Cop: Everytime when he fails to kidnap Emmet as his originally intended victim, he starts kicking the chair multiple times like a maniac while being in his childishly raging mood.
 * Victor Costa: Attempts to attack Jeanne who knocks him out cold then suffers this when he imagines the Colossus statue arriving to save him so he jumps off the crane’s hook into the hands of the statue, falling to his death.
 * Carface Carruthers: Attacks Charlie in a blind rage.
 * Scarlet Overkill: As the Minions kept messing with her plan to steal the crown and become Queen of England, Scarlet becomes more and more unhinged as the movie goes on, until she snaps when they try to get the crown back.
 * Shangri Llama: After Sid unintentionally destroyed Geotopia, Shangri Llama was very shocked and started freaking out, panicking and screaming in anger.
 * Alphonse Perrier du von Scheck: Upon seeing Arnold, Gernald & Helga escape with the footage of him burning the document, he angrily roars in a fit of an uncontrollable rage.
 * Burger-Beard: After having his magic book destroyed, he vows to clean his armpit with SpongeBob's dead body (due to SpongeBob is a sponge as Squidward pointed out).
 * Gargamel: Sometimes suffers this while making few attempts to kill the Smurfs, especially when they succesfully overpowered and outsmarted him.
 * Kent Mansley: Goes over the general's head and orders a submarine to nuke the Iron Giant, resulting his own arrest or death for act of terrorism and forces the Iron Giant to sacrifice itself to destroy the nuclear missile with explosion that only incapacitated it as it later reconstructing it's body for a long time.
 * Russ Cargill: Having gone mad with power, orders the Domed Springfield destroyed (not caring about the innocent civilians lives that would be lost). When Homer destroys the dome with the bomb, Cargill then appears and aims a shotgun at him, but not before Maggie knocks him out with a rock.
 * Claudandus: During his final confrontation with Francis, the latter angrily expresses his belief that there are good people in the world, which angers Claudandus into screaming furiously at him that are no good humans and that animals are the only good creatures on Earth. When Francis deletes the entire Felidae program, Claudandus, finally pushed over the edge, engages his former protègè in a violent fight to the death that ends with Francis killing Claudandus by goring him in mid-air with his claws, disemboweling him in the process, avenging every single cat he murdered, including Felicity and Solitaire.

Disney and Pixar

 * Chick Hicks: In the first film, Cars, where he served the main antagonist, in his breakdown, he slams his arch-nemises, Lightning McQueen and The King, as he was last but got himself on loose.
 * In Frozen, after witnessing Elsa's escape before he had a chance to slay her, Prince Hans was so furious that he soon walked through the blizzard in an attempt to destroy Elsa with any costs.
 * In Sleeping Beauty, after her plans were foiled by Prince Philip, Maleficent went into a mindless rage and became a enormous dragon in order to kill the prince relentlessly.
 * Lyle Tiberius Rourke: Furious with Milo's persistence to stop him from taking the Heart of Atlantis away with Kida as it's vessel and worsens when Hilda who he previously betrayed seconds ago shot his balloon down, Rourke begins to take his aggression out on Milo and uses an ax. He hits a glass cover of the container, with glass shards becoming embedded with the Heart of Atlantis. As Rourke holds Milo up for a killing blow, Milo cuts him with one of the shards and he begins to transform into a crystal form. Rourke still attacks, but a hence situation causes him to be hoisted into the still moving propellers, destroying him for good.
 * Professor Ratigan: When all of his attempts at taking over the Mouse Kingdom failed and is exposed by Basil, his egotism cracks and he becomes a feral rat, charging and clawing at Basil in a fit of blind and savage rage.
 * Henry J. Waternoose: Upon seeing that Sully still has Boo with him, he charges at them in a fit of controlled rage. When he catches up, not only does he claim that scaring is no longer enough, but he also exclaims that he'll kidnap 1,000 children before he'll let Monsters Inc. die and silence anyone who will get in his way. This however, caused him to be exposed by Mike, resulting in his arrest.
 * Amos Slade: He attempted to kill Tod when he assumed it was his fault that Chief got hit by the train. Later, when he finds out that Widow Tweed dropped him off at the game preserve, he and Copper break in to kill him.
 * Prince John: When Sir Hiss mentions John's mother one last time, he starts sucking his thumb and beating his serpentine sidekick with a stick, chasing him into the burning castle.
 * Lotso: Revealing his true nature by belittleing his fellow toys as trash waiting to be thrown away after Woody mentions Daisy and exposing his nihilistic nature in doing so, resulting in him being thrown into a garbage dumpster bin by Big Baby.
 * Hopper: Attacks Flik and attempts to throttle him for revealing that ants are capable to overpower his army of grasshoppers until he meets his match, which is none other than the bird that blinded him in one-eye.
 * Bill Sykes: When Fagin runs away, he screams "FAGIN!!!" in an extreme rage, then he chases Faigin's scooter with his car, driving like a maniac into a subway trying to snatch Jenny back. But Oliver and Dodger attack him, allowing Jenny to escape. Even as Sykes manages to throw them off, he turns to see a train speeding starght for him just before his car collides with it, killing him in a fiery blaze, and sending the remains into the East River.
 * Cecil Clayton: He tries kill Tarzan so that he wouldn't interfere with his plans to sell gorillas. Things only get worse when Tarzan only shattered his gun and was later have him incapacitated with vines, where he completely snapped and slashed everything around him. Realizing that he would killed himself, Tarzan tries to stop him, only for the latter fall to his death with a vine that gor stuck on his neck, and ultimately shattered his neckbone upon impact, if not resulting decapitaton considering the height of his falling.
 * Donald Duck: Despite being a "protagonist", he has a very infamous breakdown in "Mickey and the Beanstalk", by devouring plates and nearly killing a cow all while in a psychotic rage. This is justified since he was starving for an extended period.
 * Shan Yu: Flies into a blind rage several times, especially when he slashes Mulan's side for burying his army in an avalanche (which left only few of them survived) and chasing her onto the rooftop in the final climax, smashing everything in his path.
 * Judge Claude Frollo: When Esmerelda chose to die than be his lover, he attempted to kill her. He then attacked the cathedral. When Quasimodo came to her rescue and took her in the cathedral, Frollo breaks in, directly defying the Archdeacon and flinging him down a flight of stairs. The evil judge then makes an attempt to kill both of them. In this breakdown, he also released his 20 years old repressed hatred on Quasimodo.
 * AUTO: Attacks WALL-E and crushes him in the Axiom's machinery so no one can return to the earth.
 * Governor Ratcliffe: After Pocahontas makes peace with the settlers and her people, Ratcliffe takes matters into his own hands and attempts to murder Chief Powhatan, but shoots John Smith instead.
 * Professor Z: When the bomb strapped to Mater does not explode due to being out of range, Zundapp repeatedly presses the useless detonator button to no avail. When Finn McMissile apprehends him, he angrily asks McQueen why his weapon failed to destroy him.
 * Cruella De Vil: Blindly chases the Dalmatians in an attempt to recapture them.
 * Ursula: After losing her pets, Ursula becomes enraged, grows to a massive size via the magic of the Trident and seizes power over the ocean, then attempts to kill Ariel before being stopped and killed by Prince Eric.
 * Monstro: After sneezing twice, as a result of a fire Gepetto and Pinocchio made to escape from his mouth, Monstro becomes enraged as he puts out the fire in his stomach and gives chase to get his food back.
 * Ronno: Chases Bambi through the forest in rage after our hero shoves him.
 * Syndrome: He wanted revenge on Bob Parr for not letting him be his sidekick and later, kidnapped Jack-Jack to help him get revenge in the future, only to backfire as Jack-Jack reveals his powers and was saved by Helen. In response, he angrily vows to get Jack-Jack, only for Bob to throw a car on his jet that resulted in his death by the getting his cape stuck in his jet's propeller vane, effectively avenging the deaths of superpowered humans that he killed and ended his crusade agains Supers once and for all.
 * Kron: He attemped to kill Aladar for interfering with him thrice.
 * Percival C. McLeach: When Cody warned him that his mother will call the rangers on him, he attempted to kill him so that she wouldn't tell them about him. Otherwise, he would get arrested.
 * King Candy/Turbo: When she starts to gain on him, the king goes out of his way to attack Vanellope Von Schweetz head-on in an attempt to knock her off the track. She glitches to reveal that King Candy is actually Turbo. After fusing with a Cy-Bug, he attacks Ralph in an ill-fated attempt to prevent him from saving Sugar Rush, and every game in the arcade.
 * Bradley Uppercrust III: Is so obsessed with winning that he is willing to severely injure or even kill his opponents and even leaves his right hand man tank to die in the burning wire and fabric logo. Goofy and Max help Tank escape and Max beats Brad to the finish line. Tank then turns on Brad for betraying him and slingshots him into the Xgames blimp.
 * Dr. Facilier: He angrily vows to make sure Tiana becomes the frog for the rest of her life after she refuses his offers, which during the breakdown he make a fatal mistake: He inadvertly gives Tiana an opening where she shoot out her frog tongue on his talisman and shatter it (causing him to suffer another breakdown about his talisman's desecration), which causes the voodoo spirit who he worked with took his soul as the payment of his debt.
 * Gaston: Vows to make Belle his trophy at all costs, even includes killed The Beast whom actually the man whom became Belle's future true love that cursed into werewolf-like monster due to his past deeds.
 * Forte: Knowing that there will be a chance for the spell to be broken, Forte, refusing to 'fade into the background', decides to bring the whole castle crashing down, intending to kill everyone inside, since no one can fall in love if they're dead.
 * Jafar: In the original film, he has this after learning that Aladdin took back the lamp at the cave of wonders. And then there's his mad laugher moment after the Prince Ali reprise, his spouting off his Hurricane of Puns during the climactic battle, and his Big "NO!" when he realizes that he's a slave to the lamp after becoming an all-powerful genie. Subverted earlier on when Jafar starts laughing maniacally after being exposed for the Evil Chancellor he is. Iago thinks he's cracked, but in reality, he realized that Prince Ali is actually Aladdin.
 * In The Return of Jafar, Jafar is enraged to see Aladdin still alive after his plan to have him beheaded fails (thanks to Iago releasing Genie from the orb).
 * Sabor: Ultimately taking the more agressive attempt to kill Tarzan when the latter reveals his combat skills to protect his gorilla clan.
 * Hades: Hades obviously losing his composures when discovered that his minions, Pain and Panic, proved not competent enough to render the baby Hercules wholly mortal by having the baby not drink the whole potion until the last drop that results him mortal but retained his God powers. As he discovered this after witnesses the young Hercules defeated Hydra, he severely punished them as severe as possible includes toasting their head alive. His final breakdown was when he was extremely horrified when witnessed Hercules' attempt to save Meg's soul led him to regained his Godhood, in which he tries to save himself by begged for mercy, only to be tossed into the River of Styg and trapped for all of eternity. Although, given that he is fully aware of both his bad tempers and breakdowns where he would immediately try to remain calm and maintain composure as much as he can (which made him considered the villain whom 100% sane), he appeared have the relatively short duration of his breakdowns in spite of his hot-headed personality.
 * Scar: When he finally admits to Simba he killed Mufasa, and now is cornered by his enraged nephew. Scar pathetically begs for mercy, trying to blame everything on his Hyena Henchman (not knowing they overheard). After Simba defeats him, Scar is horrified to discover that the Hyenas had overheard him blame them on everything and are now circling him with furious hunger. Scar begs for mercy but the hyenas had had enough of his lies and mawl him alive.
 * Stinky Pete: Attacks Woody in a maniacal rage, screaming that Children destroy toys, and even goes so far to prevent Woody being saved, resulting the struggles that resulting his defeat.
 * Dr. Phillium Benedict: Cries and screams in his villainous defeat over his now officially ruined plan, as Vince manages to destroy the entire laser beam device with a baseball that TJ orders him to.

DreamWorks

 * Kung Fu Panda
 * Tai Lung: With his composure really starts to fall apart once he sees the Dragon Scroll he so coveted. Instead of fighting intelligently and using the environment to his advantage, like he did in every fight before, he single-mindedly pursues the scroll, losing more and more of his cool as Po starts to give him problem: Po's manner in fighting him was ironic as he uses the environment and his intelligence like Tai Lung himself usually did albeit in more comical manner as his competence not as good as the latter. After he obtains the Dragon Scroll and finds it to be blank, he suffers from this full out and it just gets more intense after he discovers his pressure point technique to be ineffectual against Po thanks to his fat that shielded him from the attack, causing him to throw all semblance of strategy and martial arts mastery out the window. After getting beaten and barely able to get up and stumble around, he just keeps rambling and trying to fight back, leaving him in a vulnerable state when Po finished him with Wuxi Finger Hold technique.
 * Lord Shen: Po appearing as Shen is about to sail to triumph seems to result in the peacock finally losing it. He becomes so wrecked with rage, that he is willing to fire on his own fleet to clear out all obstacles and casually knifing the Wolf Boss when he refuses. This results in Shen refusing to cease using his cannons even when Po has perfected the catch and return technique. When Po confronts him on his ship after crippling it, he finds Shen completely stunned by both the fact everything he created has been destroyed and the fact that Po managed to overcome his traumatic past and find inner peace. When Po explains it to him, Shen snaps and tries to kill Po in an insane fury, but during his blind rage, Shen accidentally slashes through the ropes holding up his destroyed cannon, causing the heavy weapon to topple over and fall towards the wicked peacock. While Po leaps to safety, Shen, seeing he has finally lost, makes no attempt to get out of the way and closes his eyes as he is crushed to death by his own cannon and obliterated by the resulting explosion.
 * Kai: loses it when Po manages to drag them back to the Spirit World. Not only is he clearly furious, nearly all the comedy in his character vanishes. He charges at Po in an insane rage, but Po willingly inserts his chi into Kai's chest. Kai's joy promptly turns to horror as Po's chi overwhelms and obliterates him, being destroyed by the very same power he sought to obtain.
 * Shrek:
 * Lord Farquaad: Already enraged at Shrek interrupting his wedding with Fiona, but upon Fiona revealing her ogress form, Farquaad snaps and orders his guards to imprison her and Shrek and sought to be a king by force. However, Shrek manages to get a hand free and whistles loudly, and Dragon bursts through the window and swallows Farquaad in one gulp, while the congregation cheers.
 * Fairy Godmother: Infuriated by the romance between Shrek and Fiona, she throws a curse at them only for King Harold to intercept and reflect it back at her with his armor, disintegrating her into thousands of bubbles.
 * Prince Charming: Enraged that Artie encouraged his fellow villains to preform Heel-Face Turns, Charming tries to kill Artie, only for Shrek to intervene and toss Charming aside, and Dragon knocks over the stage tower, which falls on top of Charming, crushing him to death.
 * Rumpelstiltskin: Determined not to let Shrek reclaim Fiona's love for him and nullify Rumpel's contract, Rumpel becomes more and more enraged in his determination to keep the alternate timeline the dysphoria it is. When Shrek succeeds in reclaiming Fiona's true love's kiss, nullifying the contract, Rumpel starts begging for more time like a hysterical baby as his whole alternate reality disappears before his very eyes.
 * General Mandible: Upon realizing all the workers he tried to drown reach the surface, he tries to kill Z, but Mandible's second-in-command turns against him and helps Z & the others saying that it is truly for the good of the colony. Mandible then snaps and charges at Cutter, but misses and tackles Z. They both fall and Mandible dies as he falls onto a root, which impales him.
 * Mrs. Tweedy: In a blind rage, Mrs. Tweedy climbs the string of lights. She prepares to kill Ginger by striking her with her axe, but her rage was eventually used by Ginger for her own advantage in the desperate moment: The hen tricked her to cuts the string instead, causing her to fall into the chute of the pie machine.
 * Chantel DuBois: Attempts to capture and kill the animals, which leads to her downfall: When she ultimately screamed in frustration after brawled with Alex, the lion later put an end of her breakdown via humiliation with indirect help of Mort whom shot her butt with a tranquilizer bullet.
 * Rameses (The Prince of Egypt): In one of the most tragic examples, Rameses snaps after the death of his son, riding after Moses and the Hebrews and when they try to escape him through the Red Sea, he shouts to his men to kill them all. The last of him seen in the film is him screaming in rage and agony, cursing Moses.
 * Smek: He tries to hit Oh with the shusher before Officer Kyle stops him.
 * Don Lino: He chases Oscar in a fit of rage for revenge.

Others

 * Cats Don't Dance
 * Darla Dimple: This starts as her efforts to stop the animals's impromptu number in the finale backfire immensely. It ends as she reveals herself to an audience while she angrily rants at Danny.
 * Max: His emotionless facade gradually breaks down into pure sadism as he pursues Danny atop the theater, only to cower before Danny when he sees the balloon is about to pop with him still on it.

Date A Live

 * Roger Murdoch: In a vote to dismiss Westcott, Murdoch had his arm torned by Ellen Mathers, just like Westcott and Russell had planned. Then, Murdoch went absolutely crazy and wanted to destroy Westcott forever in order to avenge himself. His heartless plan is no other than throwing Satelite Humpty Dumpty towards Tenguu City, which will cause great life loss and pain. Even he had a chance to avoid the catastrophe, Murdoch denied it and declared his only aim was Westcott's head.
 * Tohka Yatogami: After witnessing Shido stabbed by Ellen Mira Mathers, Tohka breaks down in shock and sadness. Her breakdown was so intense that it made her Inverse, thus making Dark Tohka took her form just like Isaac Westcott always wanted.
 * Origami Tobiichi: In volume 10, she was later turned into a spirit by Phantom and went back in time with the help of Kurumi in an attempt to fend off the Phantom who at the time she thinks was the Spirit who caused her parents deaths, which she was proven wrong just moments after she fended Phantom away, and the truth hit her very hard as she realized who killed her parents, Origami herself. As a result, she falls into extreme despair and turns berserk, similar to but worse than what had happened to Tohka in volume 7. Upon returning from the past, the Devil Origami started attacking the hospital and the surroundings where Shido and the other spirits are at.

Dragon Ball

 * Vegeta: Vegeta's pride tends to his downfall. This was exploit during this first fight with Goku, when Goku was winning, Vegeta is furious about a "low class Saiyan warrior" could surpass him. This happening again with Frieza, when Vegeta realized he's still not strong enough and was at his limit, he launches one last attack but Frieza deflects it, unable to face his greatest failure, the once proud Saiyan prince loses his will to fight.
 * Nappa: Nappa was getting furious on how Goku could be so much powerful than him.
 * Frieza: Frieza's meltdown began when Vegeta stole the Dragonballs from him, when they were turned to down, his dreams of immortality was shattered, and focuses his rage on the person responsible for it: Vegeta. However, Frieza's biggest breakdown is his sense of paranoia of the Super Saiyan legend and it turns true when Goku turns into one when he killed his best Krillin, with him losing, he took it to extreme measures to blow up planet Namek, even fighting at 100% power, Goku turned back because he's losing power, which provokes him into firing a blast only Goku to blast him to pieces.
 * Android 19: Vegeta wanted to prove that androids can feel fear. When being overpowered and tearing his arms, this theory was proven, Android 19 runs and screams away from Vegeta as his unleashes a big blast at him.
 * Broly: When first introduced, he appeared as a quiet and gentle Saiyan. However, upon seeing Goku, he attacks him, but Broly's father Paragus uses a mind controlling device to calm him down. After another encounter with Goku, and despite Paragus' attempt to use the device to control him, it doesn't work, Broly loses it, awakening his Legendary Super Saiyan form.
 * Fused Zamasu: During their final confrontation with the Saiyan trio (Vegeta, Goku, and Future Trunks) Goku Black and Future Zamasu decided to fuse together to even the playing field. However, Future Zamasu's immortality was having a negative affect with Black's mortal body. As such, their fusion became physically and mentally unstable. Fused Zamasu fought Vegito in Super Saiyan Blue form. Vegito managed to corner Zamasu but defused at the moment they were about to finish Zamasu off. This allowed the fused kai to gain the upper hand until Future Trunks stepped in. At this point, Zamasu had lost his sanity and Trunks managed to split Zamasu in half.

Bleach

 * Sōsuke Aizen: Aizen was losing his patience during his fight with Ichigo Kurosaki|Ichigo, during his last attack he assures his lost his power but didn't know that he was being sealed, he gave one last outburst before being sealed up completely.
 * Zommari Rureaux: After realizing Byakuya Kuchiki has defeated him, Zommari loses control of himself that he praises Aizen before finally being killed by his opponent.
 * Baraggan Louisenbairn: After being hit by Soifon's second Bankai, Baragann goes berserk that he starts claiming he is a god while calling his opponents insects and then dies threwing his axe at Aizen, while cursing the latter.

Naruto

 * Deidara: Realizing he is losing to Sasuke Uchiha in spite of his ability to counteract genjutsu (the said defeat remind him with similar ones at hands of Itachi), Deidara unleashes his C4 jutsu & blew himself up in attempt to take Sasuke with him.
 * Sasori: After being defeated by his grandmother Chiyo & Sakura Haruno, Sasori's living core sneaks into a puppet resembling him & tries to stab his own grandmother, only to stab Sakura instead, while stating the katana is poisoned. Before he could have a chance to continue, Chiyo stabs him using his puppet parents in the form of a hug. His breakdown wasn't stopped right there, as he mocked Chiyo's success in saving Sakura with a ninjutsu that potentially costs her life, resulting the revived Sakura punch him on the face.
 * Hidan: After being defeated & dismembered by Shikamaru in their fight, Hidan curses him & attempted to frighten him using Jashin, only to no avail as the latter claimed he doesn't believe in such god. He blew the pit's boulders to bury Hidan alive while the latter continues to curse him. Though stated that he still alive even after dismembered and buried but would dying by malnutrition, this was enough for avenging Asuma's death.
 * Kakuzu: Even though he was planning to replace the heart Kakkashi destroyed, but when he lost his own heart at hands of Shikamaru whom tricked Hidan to do so, he quickly went ravenous about killing him, Ino, and Choji. When Naruto and the reinforcements enter the field, he regains some of his composures when reconsidering to took Naruto's heart instead, but ended up severely injured by his Ranseshuriken (though succeed in second attempt) and killed by Kakashi.
 * Sasuke Uchiha: It was apparent when he ended up attacking anyone whom stand in his way includes five Kages after recognizes Danzo, stabbed his most loyal supporter Karin and left her to die, and attempt murder on his former teammantes shows that he suffer this which doubles as act of MEH. He finally regained his composures since his final meeting with Itachi.
 * Mizuki: After escaping from Konoha Prison to exact his revenge on Naruto and Iruka Mizuki suffers few breakdowns. He has the first breakdown when he starts laughing maniacally during his conversation with Tsubaki. Later, during his fight with Iruka in the forest, he screamed at him several times, expressing his hatred towards him. Finally, after drinking a Cursed Seal Potion, it becomes obvious that he lost a huge amount of his sanity since he went ravenous about killing Naruto and Iruka.

One Piece

 * Akainu: When felt a bit eerie when Whitebeard appeared behind him, turning around he stared wide-eyed at the vengeful pirate and struggled against him for killing Ace, even using his most devastating attacks, Akainu became horrified at the still standing pirate. As he delivered a devastating shockwave that destroyed Marine Ford, Akainu cursed at him. When he resurfaced, he focused all his attacks on Luffy, however, when he got away thanks to Law, he cursed at Shanks and the Red Hair pirates for allowing him to escape. After the events at Dressrosa, he argues with Fujitora about revealing Doflamingo's sinister deeds and apologizing on the behalf on the World Government world wide, he finally concluded if he doesn't bring Luffy and Law's heads, Fujitora won't be allowed at any Marine base.
 * Donquixote Doflamingo: Due to his wealth and privileges of his status of being a World Noble forfeited by his father, an angry mob wanted revenge and when he was a child, he was severly traumatized. Doflamingo holds his father in utter compemt as he shot his dad and when he was older and discovered his brother is an undercover Marine, so he hardend his heart and verbally disowned him followed by shooting him to death. When destined to have immortality, Doflamingo wanted his brother to eat the Op-Op Fruit so he can force him to give him immortality but he fed it to Law and he knew he never gave his life up to give him that. He grows frustrated if this failure is brought up. His most biggest meltdowns during Punk Hazard and Dressrosa. When Law and the Straw Hats kidnapped Caesar, he was furious, arriving to see the marines who knew, Doflamingo was willing to kill them and Smoker. During Dressrosa, after being exposed when Sugar's curse was brokem, Doflamingo was overwhelmed with fear, rage, and despair over the loss of the country, he holds Usopp in utter compemt since he "pissed him off the most". During Luffy activated Gear 4th during their battle, Luffy turned the tables in which he was getting desperate and frustrated he was being beaten, when Luffy's haki wore off, Dolfamingo stopped at nothing to make him pay, to the point of destroying the city and attacking innocent who are in the way. Whenever he gets frustrated, veins bulge out on his forehead. He even keeps smiling because he stated he couldn't get any madder.
 * Crocodile: During his final battle with Luffy, he started to lose his composure. Reason why Crocodile's composure degenerates was when he seemingly killed Luffy, the Straw Hat Pirate captain was saved by drinking water and learned that the presence of liquid substance made him vulnerable. Crocodile's second attempt to kill Luffy was proved more difficult due to Luffy carry a large amount of water in their fight that both save his live several times and gradually weakened Crocodile, and Luffy even goes so far to used his bloodied arm to struck him down.
 * Rob Lucci: Even giving three powerful shockwaves, Luffy refuses to give up, giving Lucci a shocking expression.
 * Gekko Moriah: Gekko was severely traumatized by the loss of his crew. During his battle with the Strawhat Pirates, remembering the fate of his crew causes him to snap.
 * Buggy: During his fight with Luffy, Buggy was frustrated to know that he knows Shanks who he cursed the latter because when they were crewmates, Shanks accidentally spooked him into swallowing a Devil Fruit and losing the map of the Grand Line. After seeing Nami stealing his treasure, Buggy lunged at her ignoring his fight with Luffy. After trying to reassemble himself, Buggy found Nami tied up the rest of his body causing him to have a body of smaller parts, when Luffy delievered an attack that send him flying, he screamed.
 * Kuro: Kuro prides himself on his plans as none of them ever failed until Luffy and his crew hindered them causing him to grew furious even would go far as to kill his own crew. Once Luffy caught him and stretched to headbutt him, he screamed at the despair of his precious plan to get Kaya's fortune failing.
 * Don Krieg: Krieg was confused and horrorified that his explosive spear's tip shattered because it was his most powerful weapon. When Krieg found his armor was cracking, he started to get worried but shrugged it off as Luffy died in the explosion, only to reveal himself he's still alive making shock. After his defeat, Krieg unconsciously gets up and wents berserk, demanding to continue the battle, only to be knocked down by Gin.
 * Chew: He underestimated Usopp which resulted in him getting fooled that he was about to get hit by a rubber band and getting his body covered in alcohol making him lose his temper.
 * Kuroobi: Kuroobi was furious that Sanji forced him onto dry land by blowing air in his gills, he couldn't see straight causing him to be taken out by the cook.
 * Arlong: He gets easily angered as he nearly goes on a rampage after being attacked by Usopp and has to be dragged back to his base by his crew to prevent him from destroying the whole town. During his fight with Luffy, Arlong, because of fishman DNA being of a shark, went into beserk state that made him fight reckless and destructive, even seriously damaging his own headquarters building while attacking Luffy. Arlong was even shocked to find Luffy breaking some of the blades of his Kiribachi after realizing he couldn't move it and destroying some of the maps Nami made. After Luffy bended his nose and was about to destroy his base, Arlong furiousy doubted, while fixing his nose, that his base can't be destroyed by a human like the Straw Hat Captain.
 * Ms. Valentine: She as furious upon the Straw Hats interferance with Boroque Works operations while hitting Usopp than jumped to break his neck into a million pieces.
 * Mr. 5: He was furious upon the Straw Hats interferance with Boroque Works operations as he took as mocking them. Upon Usopp tricking him into swallowing a hot tabasco, he was furious that he was being mocked.
 * Ms. Goldenweek: Though, did not show any signs of panicking when their plans were ruined, she was aware of the situation, upon Carue spotting her, she screamed when he attacked her.
 * Galdino: He was furious that his wax sculpture was melting cause of Luffy and stated for his unappreciation for artistic creativity.
 * Ms. Merry Christmas: Was furious that she was tricked when Usopp's giant hammer was really fake. During the battle, when Ms. Christmas was bringing Usopp to Mr. 4, Chopper lifted her into his horns and begins panicking that Mr. 4 is gonna hit her instead.
 * Mr. 4: When he hit Ms. Merry Christmas by mistake, he was shocked.
 * Paula: Was angered when Nami electrocuted her. She than charged at her but fell into her attack screaming on "What have you done to me?!" upon being blown into a wall.
 * Daz Bones: Was shocked when Zoro took all of his attacks and survived every one of them and keep standing.
 * Foxy: despite Luffy suffering severe beatings from him, the Straw Hat Captain will to keep fighting and not staying down was leaving him severly shocked as Luffy even stated he was going to win the Davy Back Fight even if it meant killing him.
 * Kaku: he was shock to see an aura emitted from Zoro, believing it was a "God of War" and it when it happened again, Kaku was shocked again to see Zoro emitted numerous arms and heads that resemble Asura that dissolved his Tempest Kick.
 * Blueno: during his fight with Luffy, he was shocked to see that his Gear Second is making him move faster than he his and that he couldn't keep up with his eyesight.
 * Jabra: when he was hit by Sanji's Diable Jambe, he screamed and freaked out in pain that his Iron Body didn't work, however, when Sanji was in the air, he thought he got sloppy only to plead for him to stop when he fell into a trap.
 * Fukuro: Franky stopped the momentum of the spinning which left him shocked, and when he was about to unleash a Coup de Vent at maximum at his face, Fukuro began to panick and attempted to punch him off but failed.
 * Kumadori: when Chopper was forced into using his Monster Point, Kumadori attempts to use Life Return Hair Bind but when Chopper unleashed a roar, Kumadori's hair froze and he even stated himself that his "subconscious is telling him to escape with his life" but didn't listen, however, when he was injured, he stood in fear after getting up when Chopper approached before pummeling him.
 * Kalifa: she was infuriated when Nami electrocuted her. When Kalifa thinked she figured she won, she let her guard down after realizing Nami set another trap and failed to avoid it.
 * Spandam: he's cowardly and gets hot-headed easily when something doesn't go his way. He freaked out when the Straw Hats declarded war on the World Government, accidentally calling the Buster Call, was sniped by Usopp, attacked by Robin and Franky, yelled at the marines to capture the Straw Hats, and when Robin snapped his body.
 * Enel: due to Enel's overconfidence in his abilities in combat, unexpected scenarios throw him completely off-guard, disrupting his Mantra and therefore, impacting his fighting skill. As shown when he desperately tried to persuade Wiper not to use the reject dial or when he noticed that Luffy is immune to lightning, he was completely lost and visibly horrified. Given Luffy's body is made of rubber, Enel acts somewhat cowardly and unsure of himself, trying his best to avoid another confrontation with him.
 * Satori: his normal demeanor is known to dissolve into panicking when his plans go awry, as he became frantic once Luffy clings to his back when the explosion made him temporarily lost control of his Mantra and pleaded when Sanji was about to attack.
 * Hotori and Kotori: upon believing Gan Fall is dead, the two were shocked to see him again, and upon seeing Kotori and being knocked into the water, Hotori became furious that amplified his vengeance against Fall and Nami.
 * Yama: when Robin slammed him into a tree, he became utterly furious at her and tried to attack her again using Ten Axe Dials, however, when Robin literally turned the dials onto him, he panicked of what she's trying to do. Even so, Yama tried to crush her only to have his fingers snapped than hurled off a cliff, pleading for forgiveness, to which Robin mercilessly snapped him in half before crashing into the ground.
 * Vergo: Vergo is known to get mad when others don't refer to him as Vergo-san, this happened during his fight with Law in the SAD lab, and when Smoker help Law reclaim his heart, he starts to admonish Doflamingo as he even he called Vergo him Vergo-san, however, this made Vergo reached his peak as he hardened his body with Haki. Even after being cut to pieces, Vergo warned Law about not knowing about Doflamingo's past before his head is cut in two.
 * Monet: when Monet was cut by Zoro, she thought he would never hurt a woman, this belief was misled because she wasn't a proper opponent and merely a distraction. When Zoro charged at her, Monet was frozen in fear and cut in half, without Haki imbued into his swords, the thought of being killed left Monet unable to reform. In spite of this, she flew into a rage and attempted to kill him only to be taken down by Tashigi.
 * Caesar Clown: Caesar has an odd habit of being easily shocked by things that leave him dumbfounded, such as when Luffy survived his second Gastanet attack and appeared behind him unharmed. This happened again in their second fight. In their third fight, upon Luffy declaring that he does not want to see his face anymore, the scientist cried in fear, attempting to bargain him by letting him work under him, before being sent flying.
 * Jora: during her fight with Nami, Chopper, Brook, and Momonosuke, after being injured by Brook, Jora went into a rage, and even when her dimension being destroyed, Jora swore her rage towards them.
 * Sugar: after being traumatized by Usopp, due to forcing him to eat a extra-spicy Tatababasco-laced grape that him give a horrifying visage of pain that scared her into unconsciousness, Sugar has a fear of long noses or anything that resembles a long noses. This was used again to save Luffy and Law from turning into toys.
 * Dellinger: when Dellinger was cut by a sleepwalking Cavendish, he was visibly horrified at seeing his own blood.
 * Pica: Pica is very sensitive about his high-pitched voice, so much that if anyone even snickers he'll go into a homicidal rage. When his giant form was destroyed and sliced into pieces by Zoro at the Old King's Plateau, Pica remained himself that his Haki is superior than him.
 * Diamante: when Kyros overcame the spiked balls, he became visibly worried and being overpowered by him.
 * Trebol: when Law called his loyalty, even including Pica and Diamante, towards Doflamingo as being his puppet, Trebol lunged at him for the kill. After being wounded, Trebol's hatred towards him reached his peak as he tried to blow himself up along with him.
 * Jack: when Zunisha swung its trunk at him and his fleet in order to repel them, Jack began sweating in fear and watched the massive limb darken the sky above his fleet with his eyes bulging in panic.
 * Charlotte Cracker: Cracker hates it when when people eat his biscuit creations as he does not like giving away biscuits for free. When Luffy started eating his Biscuit Soldiers, he started to lose it. When Luffy attacked a new form of Gear Fourth and his Haki left his attacks with no effect, Cracker reached his peak and lunged only to sucked int and flew away.
 * Vinsmoke Judge: while Judge believes that the strong has the right to oppress the weak, he hypocritically shows great fear and despair when this is applied to himself. When the Charlotte Family revealed Big Mom's plan to massacre his entire family and rendered them powerless with Charlotte Perospero's binding candy, Judge became horrified and sank into despair, weeping in the face of imminent doom and lamenting that his lifelong ambition of taking back North Blue would be beyond his reach. While crying, Judge was mocked by Ichiji, a child that he ensured would be strong and have no emotion, while also seeing Niji and Yonji simply accepting death without any resistance and even laughing about it. Seeing this flaw in their engineered apathy, Judge accusingly stated something is wrong with them, being unable to see that it was his own selfish actions that removed their capacity to feel emotions.
 * Big Mom: Even though she is one of the almighty Yonko, Charlotte Linlin is an emotionally fragile person with a history of mental illness; most notably, a violent eating disorder in that she gets a craving for something, and if left unfulfilled, she goes on a rampage until she gets what she wants. This caused her to go berserk on Elbaf and grievously injured one of its greatest heroes, thus causing all the giants in the One Piece world to hate her. Also, she has become so greatly attached to her "mother figure", Mother Carmel that after her death, Linlin would have a portrait her at all of her tea-parties, and if this picture was damaged in any way, she would completely lose her mind and scream so loud that it would cause everyone to cover their ears.

Digimon

 * Apocalymon: Near-death after taking a pummeling from the Digi-Destined, he activates his Total Annihilation technique, a suicidal attack that nearly destroys all of the Digital World with it.
 * Digimon Emperor/Ken Ichijouji: After being told that the Digital World is real and that Digimon are living creatures, the spell of the Dark Spores breaks and Ken snaps, yelling in extreme trauma and discarding his Emperor outfit as it vanishes into data, breaking down in tears after seeing Wormmon dying.
 * Mitsuo Yamaki: Despite converting to the good side later on Digimon Tamers, he goes as far as to throttle Henry Wong when he sees that the Juggernaut program let a Deva into Shinjuku instead or erasing all present Digimon, and goes into paralysis when he sees all of Hypnos crumble before his eyes after Makuramon overloads Juggernaut. However, afterward he turns good and helps the tamers for the rest of the series.
 * D-Reaper: While it naturally raises its defenses to prevent the Tamers from reaching the core, it also re-uses ADR-01: Jeri Type's body to try and cause further psychological damage to Gallantmon, as well as demonstrating extreme sadism in doing so.
 * Akihiro Kurata: Seeing his army of Gizumon fall before him makes him go to the extreme and fuse his own DNA with Belphemon, causing him to overthrow his own creation's conscience and take over his body, manifesting as a disgusting version of his face in the Digimon's chest.
 * King Drasil: After watching the DATS team's bond with their Digimon making them stronger, as well as able to actively destroy him, Drasil's thinking starts regressing to a more primitive level as he is unable to process human emotions and connections with Digimon, constantly shouting "CANNOT COMPUTE!" over and over.

Pretty Cure

 * Dark Cure: When she first appears, she's calm, collected and a walking can of curb-stomp battle. However, once Yuri regains her Heroic Resolve and returns to action, she starts to snap, especially since Yuri's finally dumped her baggage and is fighting clearer. When we see her near the end of the series, hopped up on a major power boost, all she wants to do now is just kill Yuri and keep Professor Sabaku to herself.
 * Dune: When we first seem him, he's a smug snake who gladly wipes the floor with the other Cures and turns the Earth into a desert. Once Yuri finally drops the rest of her baggage, restored to full power and her and Tsubomi are reunited with Erika and Itsuki that things start going south for Dune. When he's nearly purified by the Heartcatch Orchestra, he flips out, grows to massive proportions and starts punching the Earth, declaring that nothing can defeat the hate in his heart.
 * Joker (Smile Pretty Cure!): At this point, it seems like he's achieved some sort of victory, gathering tons more of negative energy to revive Big Bad Pierrot. And the icing on the cake, he's created his own group of Bad End Pretty Cure, and sends them to deal with the girls for good. Things fall apart when he realizes that the Miracle Jewel he sought was just a fluke - it was just the egg form of Royal Candy. It goes downhill once the girls are able to overpower their twins and return to the real world that Joker flips out, revealing he's only doing this because he wants to sow chaos, that he has no real purpose. At the very end, a batch of the Bad End ink falls on top off him and he "gleefully" disappears and is absorbed into Pierrot.

Fairy Tail

 * Acnologia: Acnologia has numerous breakdowns:
 * During his fight the Fire Dragon King Igneel who questions him whether he fears E.N.D. after all Faces were destroyed, he furiously says he merely wants destruction of everything.
 * When Jellal Fernandes is fighting him to prevent him from hunting Wendy Marvell, Erza Scarlet and Blue Pegasus, Acnologia catches him with his sole arm with rage. After Ichiya and Anna push him into the Space Between Time with Christina he is shocked to see he is sucked into there.
 * During his fight with the remaining seven Dragon Slayers Acnologia gets angry at Natsu for saying the real dragons are gentle and then afterwards he states his desire for the destruction of the world.
 * E.N.D.: After finally awakening inside Natsu, E.N.D. takes over his body and brutally attacks Dimaria Yesta for torturing Lucy Heartfilia. After defeating her and saving Lucy, not knowing she is still affected by the former's magic, E.N.D. suffers a breakdown and moves to hunt Zeref Dragneel and only furiously uttering "Zeref". When he bumps into Gray Fullbuster who asks him whether he is E.N.D. they unhesitatingly start fighting each other in blind fury until they were both stopped by Erza Scarlet who thought Makarov to be dead due to using Fairy Law while overexerting himself.

Others

 * Zero (Pokémon): During the final battle, Zero has a breakdown and ensnares Giratina in the Icicle trap in a rage. He also relentlessly pursues Shaymin before Shaymin uses Seed Flare to escape.
 * Jagi: At the time before Hokuto no Ken began, Jagi was infuriated over the fact Kenshiro got the Hokuto Shinken successor that he wanted for himself.
 * Panik: In Yu-Gi-Oh!, Panik likes to win through intimidation, and before dueling Yugi, has a way of "getting to you and making you slip up" no matter how long his opponents can keep a level head. However, when Yugi proves immune to most of Panik's tactics, and implies that Panik is a coward by hiding in the shadows, Panik becomes extremely agitated, at one point shooting fire directly at Yugi (as opposed to around, as he did before), which Yugi casually avoids. Once defeated by Yugi, he has a "panic attack" (as Tristan puts it) and tries to incinerate Yugi out of his rage, smashing the flamethrower controls with his fist as he does so before Yugi destroys him and sends his soul to the Shadow Realm.
 * Hellmaster Phibrizzo: At the end of Slayers Next, the Demon Lord discovers much to his astonishment that the ultimate spell he succeeded in unleashing does not destroy the world, but instead summons the Lord of Nightmares, creator of the universe. He bursts into hysterical laughter before cowering in desperation, ranting over and over about his careful schemes that have gone down the drain, eventually losing his sanity.
 * Creed Diskenth: During the battle of the old castle midway through the manga, Creed is overjoyed to see Train (the primary protagonist) enter the fray, but when Train starts shooting him before casually taking his leave, he totally looses it. He first broods in despair, standing motionless and open for attacks, but when Shiki berates him for his obsession, he throws a fit of rage and violently attacks his foes. In Creed's case, his Villainous Breakdown makes him even more dangerous, as it upgrades his power.
 * Hao Asakura: After his twin brother Yoh is revived by the kind words and fond memories of his friends, Hao becomes furious to realize that Yoh's soul could not become one with him after all, and as the final battle against him continues, it becomes apparent that Hao is finally losing all of his sanity, especially when he orders his Spirit of Fire to absorb the Great Spirit. Note: this only happened in the anime and not in the manga.
 * Seta Sojiro: Before his fight with Kenshin, one of Shishio's minor henchmen told Sojiro about how he was grateful that Kenshin showed him mercy by not killing him. As this idea is strange to Sojiro, it bothers him throughout his fight with Kenshin. He finally reaches his breaking point after Kenshin asks him if he thinks he could still start over despite what happened. This causes Sojiro to remember the night he killed his family. He remembers that even though he was smiling, he was actually crying. This completely shatters his emotionless facade, and he is defeated soon after.
 * Shishio Makoto: During his battle with Kenshin, Kenshin does not die, because his friends are waiting for him to return to them, and he says that his will to live is stronger than everything else. This causes Shishio to break down and say that he is the only one stronger than everything else. He wildly attacks Kenshin while screaming that the weak are only food for the strong. However, his body temperature has risen too high due to the fact that the burns all over his body left him without any sweat glands. His blood starts evaporating, and the high temperature of his body causes him to burst into flames. He completely loses his mind in his final moments, and ends his life screaming in pain and laughing like a madman.
 * Einst Beowulf has his first breakdown in the opening of SRW: The Inspector when Axel Almer defeats him and taunts him over going to a new world while Beowulf has to remain in the old one. Beowulf then coaxes his monstrous mech/einst unit to charge Axel in his Soulgain unit while the latter is already within the teleport field. Axel fires Soulgains arm into the cockpit, seemingly killing Beowulf. When he later turns out to have survived and mutates into the final boss for the anime he has another breakdown when the heroes, accompanied by Axel and Alfimi attempt to thwart him, which ultimately leads to his demise, burning up in Earth's atmosphere.
 * Miharu Shimizu: During the haunted house challenge at the school, due to Miharu's serious obsession with Minami Shimada, her face turned red and then behaved goblin-like by talking crazy.
 * Moo: In episode Tears and Blue Skies, he initially ended up berserk against his own will due to accidently absorbing too much hatred that manifests from protagonists' hearts (except from Genki's). Then, when the revived Phoenix arises and fought him, with his remaining composures that finally burns thanks to Phoenix's presence, Moo proceed to having himself and Phoenix destroyed each other within a huge ball of light. It should be noted that his villainous breakdown is not started from rampage due to overloaded by absorbed hatred, but rater when finally confront phoenix.
 * Reiner Braun: Angered with combined forces of Survey Corps succesfully taking Eren away from him while in his titan state, and combined with Bertolt Hoover being in great peril in his hands as they surrounded by hundreds of normal titans at the same time, he wrathfully retailates by throwing most of the titans towards the Survey Corps army albeit they are after him instead.
 * Melona: Realizing the Swamp Witch's army are losing from Leina & her friends, Melona desperately summons the Great Snake Demon in an attempt to stop them, while forming its shield with Airi & Menace realize this has gone too far & retreated. Melona manages to pin down Tomoe & Claudette using the collosal beast but was soon defeated when Leina, with a help from Nanael, manages to stab the demon's eye. Aldra then arrives & manages to petrify the beast, causing it to shatter.
 * Raynare: When Issei began to have the upper hand on their fight, she loses it & attempts to flee, only to be caught & defeated by the latter.
 * Gian (Doraemon): Various on the episodes, normally due to everything didn't work as what he wanted.
 * Jean Descole: In Eternal Diva, he suffered a breakdown where he resort to destroyed the entire island to rise Ambrosia with Detra Gigant because he didn't finished the entire puzzle. When Layton finished it instead, he went into blind rage and tries to kill the archaeologist, only to fall into woods below. It's later revealed in Azran Legacy that the true cause of this breakdown was due to him in an desperate attempt to prevent Ambrosia to fall into TARGENT's hands, but Layton's interfere was made everything became worse as Layton unaware that Emmy, whom joined his adventure was a spy of the said evil organization.
 * Light Yagami: There are 3 version of Light's villainous breakdown, in which all of them due to exposed as Kira:
 * Manga Version: After being exposed and Mikami unable to help him, Light becomes increasingly distraught and begins asking for help from Misa, only to be told by Aizawa that she isn't here. He then asks for Takada and is told that she is dead. In complete desperation, Light begs Ryuk to help him by killing everyone in the room, yet Ryuk reminds Light that he is on neither side. Ryuk fulfills his promise from the beginning: he writes "Light Yagami" in his Death Note, and Light futilely asks Ryuk to reverse the process. He begins to panic, repeating in his head "I don't want to die," before the Death Note finally takes effect thus killing him.
 * Anime Version: After failed to convince Near and his allies that he wasn't Kira, he laughs maniacally and attempts to acquit himself by justifying his use of the notebook. When that fails, he tries to convince Near that the notebook the task force brought with them is a fake, creating a distraction so he can write Near's real name on a piece of the Death Note hidden in his watch. Furious, betrayed, and angered by Light's apathy toward his father's death, Matsuda shoots Light several times, leaving him badly injured and completely cornered. But before he could be arrest by everyone, Mikami suddenly commit suicide, allowing Light to escape and died in peaceful manner due to his wounds, in which Ryuk has arranged the scenario of his last moments with his own Death Note as he promised long ago.
 * Live-Action Version: After failed to arrange scenario to have his father died Soichiro with Death Note (in which revealed switch with the fake one) and L has convinced Soichiro to do so and they together with the police force to exposed him as Kira for good, he berate them for the defects of the law. Soichiro respond this by stated that law was not perfect as much as humanity does whom create it, but they still do their best to do the righteous. Unsatisfied, he called Ryuk to write everyone's name in his Death Note and laughs maniacally as Ryuk seemingly wrote their name, only to be revealed that he wrote his name instead.
 * Annie Leonhardt: When exposed as the Female Titan by Mikasa and Armin, she laughs uncontrollably for a brief, before she praises Armin for his accusations. Just then, she immediately transformed into her Titan form just as other soldiers go to capture him.
 * No-Face: In Spirited Away, No-Face, in his monster form, chases Chihiro in a fit of a controlled rage after she fed him some medicine.
 * Dio Brando: In JoJo's Bizarre Adventure, When Defeated by Johnathan and Jotaro throughout the series by losing composure as he starts using his infamous "WRYYY" and becomes self-destructive by the end of the fight.

Agents of S.H.I.E.L.D.

 * John Garrett goes into a meltdown with a massive side of soliloquy when he recovers from the first attempt in the Season One finale to kill him, only to be swatted permanently by Phil Coulson in mid-rant.
 * Grant Ward has at least three obvious villainous breakdowns:
 * In the first-season finale, upon seeing Garrett embracing his newfound power as the Clairvoyant, Ward goes into a paranoia-fueled panic over not being given any orders to follow, as he has become too dependent on following him at this point in time. He calms down, however, when Garrett returns to giving him orders and gives him permission to go after his romantic obsession, Daisy "Skye" Johnson.
 * In the second-season finale, after Agent Melinda May tricks him into killing his current girlfriend, Agent Kara Lynn Palamas (aka "Agent 33"), he has one of the calmer examples of a villainous breakdown, as he gets worked up into a brief frenzy of grief before quickly calming down again. When seen later, he is in a bar, holding a picture of Kara as he gets ready to rebuild H.Y.D.R.A., vowing revenge on Coulson, May, Daisy, Leopold Fitz, Jemma Simmons, Lance Hunter, and Bobbi Morse, all while disguising it as him getting "closure" with them.
 * In "Closure," the ninth episode of the third season, Ward nears a breakdown when he discovers that Coulson, Hunter, and Bobbi have abducted his long-lost brother, Thomas. However, upon getting the chance to speak with him on the phone, he is verbally rejected by his brother, who renounces him for killing their parents (despite their abusive nature) and their older brother, Christian. This, combined with him finding out that Thomas had only spoken with him to give Bobbi time to trace his call, results in him going into a full-on breakdown. He begins torturing Simmons (whom he has kidnapped along with Fitz) even harder than before. The breakdown continues all the way up to his death at Coulson's hands in the following episode, "Maveth."
 * The formerly-robotic, now-human Aida has a villainous breakdown in the penultimate episode of the fourth season when Fitz breaks the news to her that, in spite of her machinations to make him fall in love with her as he had done in the Framework, his heart lies and remains with Simmons in the real world. This causes Aida to immediately erupt into an insane rage that leads her into killing several S.H.I.E.L.D. agents and, in the season finale, vowing to Fitz that she will kill everyone he values, starting with Simmons (whom she believes that she does kill, only to learn that it was a Life Model Decoy of her). She is finally put down by Coulson when he temporarily dons the Ghost Rider spirit and uses its hellfire to burn her now-human body to a crisp.
 * Kree supervillain Kasius has his villainous breakdown in the ninth episode of the fifth season, "Best Laid Plans," when he is outplayed by Mack, Yo-Yo, and their friends, Tess and Flint, and learns that they have distracted him long enough to free all of the Lighthouse humans from his tyrannical control. The breakdown worsens slightly when they manage to temporarily escape from him. It continues to worsen in the midseason finale, "Past Life," when he learns of the death of his right-hand woman, Sinara, and he kills a Kree doctor who outright informs him that there is no way to revive her the way that they had done to humans. It reaches its peak when he ingests a bottle of odium, a drug that strengthens, and then kills, Kree who take it, and uses it to fight and nearly kill Mack. He is stopped when Simmons slips a slug into his ear that blocks his hearing (something that he had previously done to her), and the temporary distraction gives Mack the opportunity to kill Kasius by impaling him through the back with his shotgun axe.

American Horror Story

 * In the first season, Murder House, Tate Langdon reached his breaking point in 1994 when he set his mother's then boyfriend, Larry Harvey, on fire for murdering Beauregard with a pillow and then afterwards committed a mass shooting at Westfield High, taking the lives of 15 students, merely because Harvey had a love affair with his mother.
 * A very famous example in the series' second season, Asylum, is Dr. Arthur Arden's suicide. While in the crematory, Arden stroked Sister Mary Eunice's hair wistfully. With her gone, the extraterrestrials scornful of his achievements, his nemesis Sister Jude reduced to imbecility and his 'Raspers' experiment a failure, he had nothing left to live for. Sobbing, he laid on top of Sister Mary Eunice's corpse and flipped the switch, choosing to be burned alive with the girl he once loved.
 * In Freak Show, Dandy Mott have several Breakdowns.
 * After his torturous show was foiled by Jimmy and his friends, Dandy chased them in rage but failed to capture them. Soon, he cried and yelled in agony.
 * After Dandy took over the Freak Show and started a even more horrible tyranny than Elsa Mars, the freaks, having had enough of his abuse, stand up against him with Paul insulting him before announcing that they are all quitting. The next day, Dandy, in a mindless rage, shoots Paul in the head with a gun and then kills Penny, Toulouse, Legless Suzi, Barbara and Amazon Eve while making his rounds, leaving only three freaks remaining alive (Desiree, The Tatler sisters and Jimmy).
 * Before his death in the watertank, Dandy was greatly terrified and pledged for mercy, but was rejected even by Tattler Sisters who revealed their hatred towards him. As the water was filling inside the tank under the remaining Freaks' arrangement, Dandy cried and yelled in horror before he was ultimately drowned.
 * In Hotel, John Lowe succubed to his insanity after knowing that he became the chess piece of Mr. March and thus, unknown to himself, becoming the killer he had been chasing all alone. It drove him going further to kill the Countess as well.

Sleepy Hollow

 * After Jeremy Crane was tormented mentally by Moloch, who told him that he was merely a pawn, Jeremy, who regarded Moloch as his true father, was deeply hurt and cried crazily like a child for the first time after more than two centries.
 * By the end of "Awakening", after Abbie killed Jeremy, a tearful Katrina Crane (who had turned evil) blamed Ichabod and Abbie for her son's death. She then scolded and attacked Ichabod, but not after she travelled to the past in an attempt of slaying her fatally wounded husband.

The Walking Dead

 * Philip Blake had numerous breakdowns:
 * As they reach the army, they stop the convoy and leaves his car angry at them, ordering them to go back to the prison immediately. Martinez and Allen agree with him, but the rest of the army refuse to attack the prison again, since they are scared and want to return to the safety of Woodbury. The Governor loses his sanity and starts shooting everyone to the ground. At that point on, Allen stands up to The Governor and nearly shoots him after pointing the gun at him, but The Governor, who is unfazed, easily kills him after tricking Allen into standing down. Martinez and Shumpert only watch horrified as The Governor shows no remorse whatsoever after killing 23 of his own people.
 * When tries to convince the Governor that they could live together, The Governor says they can't. Refusing to leave, Rick instead brings out a memorable speech that  once told him that everyone is not too far gone, and that everyone can live in peace together. The Governor appears to have listened to Rick's speech, but – after looking towards him on the other side – he calls Rick a liar and strikes Hershel with 's sword, partly decapitating him and leaving both Rick's group as well as his own equally shocked; Hershel's daughters Maggie and Beth reacting horrifying. Upon retreating, The Governor notices Hershel attempting to craw away and catches him off guard before slashing his head off, killing Hershel.

Power Rangers

 * Master Vile: After the Alien Rangers defeat his latest monster, he throws a tantrum and basically just leaves in a blind rage.
 * Ecliptor: He loses it when he saw Astronema's corpse.
 * Psycho Rangers: Most of them have one expect for Black, but Psycho Red has the most severe one during his battle against the Rangers, claiming that he is the only one who can destroy Red Space Ranger and going on a mindless attack.
 * Toxica: Desperately trying to get the favor of her master, General Mandilok, she was convinced of cutting her own horn in order in succeed in kidnapping Princess Shaya without fearing being killed by the Animarium's fountain. She later learns that horns don't grow back, yet still pledges loyalty to her master, obsessed with his approval. Then her efforts are dismissed as Mandilok uses her to shield himself from the rangers' attack.
 * Zurgane: He suffers one during the finale of the Power Rangers Ninja Storm episode "General Deception".
 * Master Xandred: Nearly tears the ship apart in a blind rage when he discovers the Red Ranger is the one who sealed him away and Jayden could do it again.
 * Serrator: After Deker betrays him, he goes completely insane, firing randomly in all directions and his normal evil laugh becoming even more unhinged.
 * Prince Vekar: When the Rangers take the fight to the Armada, he absolutely flips out. This continues for the rest of the Megaforce series.

Kamen Rider

 * Kamen Rider Ryuji
 * Takeshi Asakura / Kamen Rider Ouja (TV Series continuty): Asakura originally entered the war to kill Kitaoka, but when he finally, technically achieved his goal by killing Zolda (who was, in truth, Goro Yura), he went mad with dissatisfaction and mindlessly ran into the ambush of police, finally having himself killed by gunfire.
 * Kamen Rider Ex-Aid
 * Parado / Kamen Rider Para-DX: Parado originally acted playful and cheery, but he was horrified when he saw Masamune Dan killing Loverica permanantly. During his battle against Ex-Aid in Hyper Muteki form, Parado faced defeat and eventually, his death. Before his first death, Parado was so horrified that he cried in terror and agony before he dissolved into data. After Emu brought him back, Parado realized the extent of vileness in his actions and crumbled on the ground, crying in remorse as he finally realized how precious life was.
 * Masamune Dan / Kamen Rider Cronus: Masamune has three breakdowns overall.
 * First, after Emu used Hyper Muteki to achieve his final form, Masamune met his first defeat and gone into an unhinged insanity, storming back to Genm Corp's headquarters and threatening Hiiro into discontinuing Ex-Aid or facing Saki's data being deleted right in front of him.
 * Second, after Emu and Parado destroyed his Gashat together, Masamune reached his breaking point, using Restart to restore his Gashat and wipe out Hyper Muteki's existence.
 * Third, after his failure over restarting Kamen Rider Chronicle once more, Masamune slammed his fists on the ground and turned completely insane by witnessing Gamedeus appearing. He tried to turn the table by rewriting Gamedeus' setting, but it faced failure once more after Emu weakened Gamedeus with the Doctor Gashat. Finally reached beyond control, Masamune arrived and destroyed Gamedeus, before absorbing its data and causing his original personality fully shattered, turning him into G-Cronus and later Gamedeus itself in process.

Super Sentai

 * Chikyuu Sentai Fiveman
 * Doldora: After discovering that she was used by Vulgyre, who used Empress Meadow as his ruse to deceive her and her companions, Doldora was so shocked that it reduced her into insanity. She started to babble about her suffering from such revelation and started to throw away her helmet, laughing and crying madly at the same time. This was eventually stopped after Vulgyre fused her and Zaza into Baradorugin, a mindless puppet for him to manipulate.
 * Hyakujuu Sentai Gaoranger
 * High Duke Org Ura: The moment when GaoFalcon showed up is where Ura is starting to lose his confidence and ends up screaming after being struck down by the Hyakujuuken.
 * Doubutsu Sentai Zyuohger
 * Quval: After finally making his move against Ginis and losing badly, Quval decides to amuse Ginis with more destruction in hopes of staving off his wrath. When the Rangers try to talk him out of trying to do to Earth what was done to his world, he tells them in no uncertain terms that he doesn't care what happens to Earth as long as he can save his own skin.
 * Azald Legacy: After having his core installed with three Continue Medals by Naria and got enlarged, Azald Legacy was angry that Ginis used him as a pawn and was reduced into a mindless rampaging beast who attacked and destroyed everything on sight.
 * Lord Ginis: Ginis mainly maintained a sophisicated and cold-hearted attitude in the overall series. However, he fully lost his composure in the finale. As soon as Zyuohgers discovered that Ginis was made of an assemble of Moebas, which Ginis showed disgust upon, Ginis attacked them in blind fury and tried to kill them all for discovering his most shameful secret. It turned even worse when Naria appeared to show her compassion over him by shielding him, only resulted Ginis murdering her out of spite and claiming the worst insult for him would be compassion. He reached his breaking point after his connection to the Earth was severed, leading to his eventual defeat.

Others

 * Morgana Pendragon: Having at least two records on this:
 * Lashed out on Merlin and Gaius whom previously combined their powers to defeat Morgause and ended her brief reign over Camelot by causes the whole castle shakened by her magic, but still retained her composure because she intended the said outbursts of magic to escaped.
 * After Mordred's death, Morgana personally goes for confront Merlin personally out of believe that she could handle the Emrys, but forgot to count that the hero's Excalibur possesses powers to killed her in spite of her powers that prevent her from dying by conventional means that led to her downfall.
 * In Once Upon a Time, Rumplestiltskin absolutely flips when he thinks that Belle was working for Regina Mills in a plot to take away his powers.
 * In Season 4 of Arrow, Damien Darhk completely loses his mind upon the death of his wife. He begins ranting that all of humanity deserves to die and that they can’t be saved to the point that even Malcolm Merlyn, a magalomaniac who tried to destroy a part of Star City and is singlehandedly responsible for at least 550 deaths, including his own son, was disgusted.

Sons of Anarchy

 * Clay Morrow: Having had enough of the sermon, Clay interrupts it questioning how long it was since Jesus was crucified and he also questions how Jesus would be the very thing that would bring all of man together regardless of sin. He then makes a sermon of his own preaching about the woman's genitalia to other inmates. Regardless of the guards telling him to sit down, Clay continues becoming more erratic about his sermon. He bites off a guard's nose while being subdued. He spits the dismembered nose at the priest proclaiming that he knows the truth and that the woman's genitalia has set him free while breaking down into maniacal laughter.

Nintendo

 * Super Mario Bros.
 * Bowser: During the games, he continues to kill the Mario Bros. and other allies in a rage.
 * Bowser Jr: In New Super Mario Bros U, he loses his temper just seeing Mario enter his room. This happens every time.
 * Kamek: Kemek loses his temper several times. In Yoshi's Island, Yoshi consistently stymies his efforts to collect Baby Mario, leaving him so agitated that by the time they reach Baby Bowser's room he can barely form coherent sentences.
 * King Boo: In Luigi's Mansion: Dark Moon, he (as Professor E. Gadd pointed out) flipped out when the Big Boo was defeated and summoned a Paranormal Portal to unleash an army of ghosts as a desperate act to slow Luigi down. His breakdown is further exacerbated after Luigi defeats the Tough Professor and makes off with the final piece of the Dark Moon. King Boo then intercepts the Pixelator and pulls him back into his illusion, The breakdown continues as the fight wears on.
 * Smithy: He loses his temper when Mario and his allies beat him in the first round, sending him into an unstoppable and monstrous rage.
 * Doopliss: He absoulety loses his temper when Mario tells him his name.
 * Shadow Queen: She suffers both a literal and mental breakdown at this point. Mario drives her to this once he gets his climatic second wind kicks in. At first, it may not show up, but once you chip off enough of her HP during the final battle, she really starts to break down.
 * Dimentio: He becomes an Omnicial Maniac after being defeated by Mario and company for the last time.
 * Princess Shroob: After her ship is downed, the Shroob Princess emerges from the wreckage furiously calling Princess Peach useless and declaring the kingdom is hers, and she will destroy everyone.
 * Antasma: His anger at Bowser's betrayal makes him go from confident to screcehing mad as he vows his revenge against the Koopa King. He then attacks Dreambert in retaliation.
 * Rabbid Kong: He freaks out whenever his pile of bananas drops through the grate.
 * Phantom of the Bwahpera: His defeat leaves him in a melodramatic, sobbing tantrum, pounding his fists against the floor and clutching his chest like he's dying.
 * Star Fox
 * Andross: After he is banished, he lets his anger lead him to vengeance. Andross then plans his attempt to get back, but Fox beats him every time.
 * Legend of Zelda
 * Ganondorf: Ganondorf suffers multiple breakdowns when he is defeated in one way or another.
 * In Ocarina of Time, after he fails in his attempt attempt to bury Link and Zelda with his castle, Ganondorf becomes so enraged that he uses the Triforce of Power to transform into Beast Ganon for the first time. As Ganon, he is a beast of pure rage and power with no strategy aside from attacking Link. When he is defeated again and sealed away by the Seven Sages, he reverts back to his human form cursing his jailers and vowing revenge on their descendants.
 * In Wind Waker, he breaks into insane laughter when his plans were foiled by the King of Hyrule. He then proceeds to attack Link, who eventually defeats him in the forehead with the Master Sword, turning Ganondorf to stone.
 * In Breath of the Wild, he's become more of a walking disaster and living incarnation of a hatemonger than a real character, intending to destroy the world instead of conquer it. As the final battle goes on he even gives up on trying to properly revive himself just so he can make sure his old foe Link dies.
 * Skull Kid: He talks a big game when Tael tells Link to brings the four giants to Clock Town, saying that they couldn't stop him even if they were there, but once he sees Link play the Oath to Order, hears them bellow response, he completely freaks out.
 * Majora's Mask: Once Majora's Incarnation realizes it's no longer winning its "game", it flips out, represented by its final transformation into Majora's Wrath.
 * Zant: He completely loses it once Link reaches his throne room, and he breaks down even more when their fight goes on, as his attacks get even more unpredictable as he is on his last hits.
 * Ghirahim: He loses his temper whenever things doesn't go his way. After Link defeats him for the second time, he stops pretending to be Affably Evil and starts acting like a homicidal demon he really is.
 * Princess Hilda: At the start of the final battle with Yuga, she remains as clam and stoic as before, but when Yuga is beaten for the first time, she orders him to give her the Triforce of Power so she can fight Link herself. The breakdown gets worse when Yuga reveals his betrayal. By the time he's defeated, she's reduced to screaming and shouting and nearly attacks Link and Zelda. Hilda's breakdown is further exacerbated when Ravio reveals he abandoned her to find a hero to stop her scheme.
 * Cia: She undergoes a gradual one that spans from meeting Ganondorf all the way to the final battle with Link at the Valley of Seers.
 * Metroid: Mother Brain: She kills the Super Metroid in a fit of anger After the it attacks her and saves Samus from the brink of death. Then Mother Brain realizes that the Metroid has given Samus the Hyper Beam, and she frantically tries to destroy the bounty hunter.
 * Earthbound/MOTHER
 * Giygas: He ended up going insane and ended up turned into nothing but madness when his powers increased.
 * Porky Minch: He gives out a massive motive rant during in Chapter 8.
 * Pokemon
 * Courtney: After Maxie is defeated and the team's plans foiled, she begins to visibly livid and starts speaking fully-formed sentences.
 * Matt: His actions in the Delta Episode.
 * Cyrus: He suffers a rather impressive one after being defeated the Distortion World.
 * Ghetsis: He had multiple of breakdowns throughout the series.
 * He starts to break down even before his defeat -- he is clearly gone mad after N loses to the player character and his challenging of the player can even be taken as being in denial over his "perfect plans" failing.
 * After the player defeated Kyurem, he gets so frustrated that his battle animation shows him stamping his cane several times until he slams it so hard, it plants into the ground. Afterwards he starts absolutely raving at the player character and N, panting from loss of breath and possible heart failure once he's done.
 * In Ultra Sun and Ultra Moon, he is from a reality where he never had his original breakdown. When defeated, he has it, almost word-for-word, with some new additions for good measure.
 * Lysandre: After defeating/capturing the Legendary and defeating him a third time, he files into a rage.
 * Lusamine: She undergoes a gradual one throughout the last part of the main story in Sun & Moon. After her first defeat, she's annoyed by the player character's interference with her plans, but still appears relatively cool-hearted. During in the Ultra Space, she's visibly livid and angrily screaming at the player character and Lillie. This ultimately culminates in her fusing with Nihilego, which leaves her not only unable to speak coherently but also ina much more violent state of mind.
 * Kirby
 * Queen Sectonia: The entirety of her second battle is basically this. For the majority of the fight, she remains as calm and elegant as usual, but after being beaten back the first time, she attempts to squeeze the life of Kirby in a rage. Then Dedede and Taranza save Kirby in a matter of moment and give Kirby a Hypernova ability, at which point she pretty much snaps and tosses every attack she can throw at Kirby as the pink puffball tears through her defenses and eventually defeats her. By the time of the "Soul of Sectonia" battle, she had lost everything but her vanity, and the defeats she has suffered have reduced her into a giggling madwoman who will stop at nothing until she has Kirby's head on a platter.
 * President Haltmann: Has a big one after his foe Kirby defeats him, where the cordial and polite CEO is reduced to a ranting screaming mess. He then threatens to use Star Dream in his attempt to eradicate all of Popstar.
 * Star Dream: During the final segment of the battle, when Kirby charges at Star Dream in his Robobot Armour and prepares to drill into him, Star Dream panics and throws up heart-shaped barrier after heart-shaped barrier in front of his face to slow Kirby down, then attempts to shoot him down with lasers when the pink puff starts drilling.
 * Hyness: Went into a long motivation rant about how he wanted to revive his Dark Lord who would help him get his revenge.
 * Kid Icarus: Hades: During his final battle with Pit. At the beginning of the battle, he's his usual self. But as the fight wears on and Pit powers through everything he throws as him, his normally calm and smug demeanor starts to erode, which all comes to a head when Medusa attacks him, where he pretty much snaps and drops his polite persona altogether.
 * Xenoblade
 * Xenoblade Chronicles
 * Lorithia: When she starts getting low health during her boss fight, she starts to realize the not only is she about to die, but Zanza's promise of her being made immortal was only half-true. The breakdown comes to a head once Kallian rebels and finishes her off.
 * Egil: Completely heartbroken when Meyneth made it clear she's not on his side anymore.
 * Zanza: Start to have one midway through the final battle, centered around the fact that he can no longer see the party's future, but Shulk can still see his. By the time Shulk breaks out the True Monado, Zanza's breakdown goes into full-swing.
 * Xenoblade Chronicles 2
 * Malos: Becomes increasingly more unhinged in the final battle, where he drops any sense of calm he has and angrily shouts that he will burn the world unless Rex stops him.
 * Amalthus: As Jin chills him out to absolute zero, Amalthus loses all composure, admits to himself he was not the Architect's chosen one, and begins beseeching the Architect directly for providence before being reduced to a whimper.
 * Splatoon
 * DJ Octavio: He undergoes one when his beats are replaced by the Squid Sisters' melody during the final phase of his fight.
 * Commander Tartar: Near the end of Octo Expansion, he starts to display visible anger as Agent 8 continues to make their way towards the surface. He continues to express more as Agent 8 manages to cover his statue weapon in ink.
 * ARMS: Dr. Coyle: She throw a tantrum when she loses, destroying Hedlok, ranting, and teleporting out in a huff.

Capcom

 * Mega Man
 * Classic: Ra Moon: When Mega Man destroys him.
 * X: Crystal Snail: When X knock him out of his shell with a Magnet Mine, he goes nuts and starts bounding around the room and dashing about trying to get back to it.
 * Street Fighter:
 * F.A.N.G: As the Cinematic Story Mode progresses and Operations C.H.A.I.N.S. starts to unravel, he becomes increasingly frantic and agitated. By the time the Black Moons are disabled and he fights Chun-Li for the final time, he's reduced to a screaming, ranting mess, furiously shouting he'll kill everyone.
 * Kage: When his opponent Ryu refuses to fight him and accept that he shouldn't have cast him aside, he loses his mind. When Ryu decides to treat him as a separate being entirely, Kage completely loses what little composure he has in his mind and fades away screaming, unable to comprehend his own existence anymore.
 * Devil May Cry
 * Arius: He becomes more loopy when he returns as a demon.
 * Arkham: After being defeated by Dante and Vergil, forced to changed back to a normal human and mortally wounded. He's confronted by his daughter Lady. He feebly tries to rationalize his action but only comes out looking like a selfish prick pathetically throwing a temper-tantrum at the power he lost. This reaches it's apex when Lady put a gun to his head to finish him off as he can only scream in terror.
 * All of the villains from the Ace Attorney games, particularly when they are exposed on the witness stand or at the prosecutor stand. These examples are noteworthy:
 * Manfred Von Karma: In the game, Von Karma slams his fist into the prosecutor stand and bellows Edgeworth's name in rage while images of the DL-6 Incident flash behind him. He then begins to slam his own head against the wall behind him, getting faster and faster by the moment.
 * In anime version, Von Karma's Breakdown was cut short, only showing him screaming and failed to made a finger snap. After his confession, Wright pointed out that it was the truth which defeated Von Karma, before the latter snapped his cane and collapsed on the ground like a broken man. The anime version of Von Karma's breakdown completely omitted the scene of which he bumped his head on the wall again and again.
 * Frank Sahwit: Throws his toupee at Wright and then froths at the mouth as though he had rabies, before collapsing.
 * Dee Vasquez: A mild example, once her role in Jack Hammer's death is proven, she squeezes her pipe so hard that she breaks it.
 * Richard Wellington: Pulls his scarf so hard his face turns blue and he squeezes himself into loss of consciousness.
 * Gaspen Payne: He complains about his perfect record in Khura'in getting ruined. His crown then starts falling backwards and drags his toupee with it, revealing his bald spot.
 * Jacques Portsman: When pressed, he starts biting the medallion he's wearing nervously. When the player expose him as the murderer, he eats it.
 * Godot: A very tame in comparison to previous ones, after he is exposed as Misty Fey's killer his visor which was smoking blows up. After Phoenix points out the obviously, his knife wound reopens invoking tears of blood.
 * Bansai Ichiyanagi: When he accidentally sets his beard on fire with his lighter, he's able to douse it by using tears collected in his goggles. During his breakdown, however, he doesn't react quickly enough and he presses way too hard on his lighter, causing it to shoot a towering column of flame before burning off his beard and hair.
 * Matt Engarde: Though it is somewhat same, Matt has two various breakdowns after he was threatened by De Killer and was about to meet his verdict. Player is asked by judge to choose the verdict for Engarde himself. If Matt called not guilty, then he gets scared for his own life and he scratches his own face violently several times while frantically screaming that he is "guilty". When he finally stops, his face is covered in wounds and his hands are dripping with his own blood. In case Engarde is called guilty by Phoenix Wright, Matt becomes shocked with the verdict of his lawyer spoiling his image, who explains him that any way Engarde wouldn't be able to hide from his crime - either he could go to prison or meet the end by the hands of Shelly de Killer. Matt violently scratches his own face, being desparate and mad about his verdict.
 * In anime version, Engard's breakdown was mildly altered, showing he scratched his face two times under the same circumstances, first after he found out that he was doomed whether what the verdict was, and then finally after he received his guilty verdict.
 * Dahlia Hawthorne: Dahlia had two breakdowns and are both considered to be the most unsettling breakdowns in the entire series, unlike many others that are played for laugh.
 * In "Turnabout Memories", she begins pronouncing Mia's name in anger, then turning her head to the camera, her eyes glowing in wrath while the butterflies that usually surround her burst into flames. Second later, however, she regained her composure and smiled at everyone.
 * In "Bridge to the Turnabout", when Phoenix and Mia finally corner her, the ghost of Dahlia (while possessing Maya) lands her head on the stand while holding it with her hands. She then screams in agony while her spirit leaves Maya's body, its hair flowing in every direction like fire and its eyes glowing evilly. She then disappears in a burst of blue flames in the shape of a Magatama while images of her crimes flash behind her.
 * Furio Tigre: After Phoenix tricks him into proving himself the murderer, he scream so loudly that the lights go out.
 * Seishirou Jigoku: He grips the witness stand with both hands and shakes violently. Then he raises his hands and smashes the stand, and the remaining parts of the stand then disappear by flying up into the air, after which he looks up while in a hunched stance.
 * Mr. Reus: The background turns to a red curtain, as he begins his show. He shows off masks of the four other members of Troupe Gramarye, one by one and burns them, but when he tries to make Trucy's mask appear, he reaches his own twice instead (the second time, the mask has been bloodied and lets out a creepy laugh). He shakes it off but then becomes frightened and then blinded by multiple spotlights. After it ends, he collapses, stunned.
 * Nearly all of the villains from the Dead Rising games mainly due to the zombie outbreak:
 * Harry "Zhi" Wong: After being defeated by Nick he recalls being fired from his job, his wife leaving for a "guy who sells refrigerators", his kids being disrespectful to him, and now a zombie outbreak. He curses the gods for forsaking him, and then while laughing in an insane manner, decapitates himself before Nick could stop him.
 * Albert Contiello: After being injected by his own syringe he starts to hallucinate several zombies and constantly yells at them telling to get their hands off his harvested organs. The zombies approach him and, in his mind, proceed to kill him. In reality however Albert cuts himself with is saw and brutally pulls out his organs until he dies.
 * Resident Evil
 * Albert Wesker: Having his evil plan to send missiles full of Uroboros virus across the entire planet failed by Chris and Sheva's efforts, he smashed one of the missile's canister full of Uroboros virus and allows the virus inside mutated him to the point that he developed deadly tentacles armed with shards and circuits from the said missile. His breakdown ultimately put to an end by both agents.
 * Derek C. Simmons: After being betrayed & mutated by Carla Radames, Derek goes berserk and blames Leon & Helena for it. He loses it more when The Family decided to abandon & replace him, causing him to try to kill both presidential bodyguards. Each time he is defeated, he mutates where it resulting him gained more stronger forms in his disposal and continues to attempt to kill Leon & Helena with those newfound combat forms, only to fail as they manages to defeat him, even with a help from the real Ada Wong. He is finally put to an end when they shoots Derek with a rocket launcher that was a gift from Ada.
 * Carla Radames: After being left for dead by The Family, the real Ada Wong confronted her corpse & talked to her, only to come back to life & mutate into a huge slime monster that took over the aircraft carrier. She tries to kill Ada all over the ship using horrendous clones of herself while declaring her a "fake" with Carla claiming she is the "real Ada Wong". She was put out of her misery when Ada shoots throught her mutated form, causing a leak of nitrogen gas that froze her new body and was shattered for good.
 * Lisa Trevor: When she confronted Chris and Wesker in Jessica's tomb and opened her casket, Lisa became hysterical upen see her corpse and threw herself into a nearby pit. Sadly, she was too invincible to die in such way where Wesker ultimately put her out of her misery by leave her to die in the mansion's explosion.
 * Asura's Wrath: Chakravartin: After being brutally attacked by Asura, Chakravartin screams angrily and frantically throws away his staves and throws his multiple fists at Asura. He managed to succeed in destroying most of Asura's arms but was knocked back. Annoyed, he decides to transforms into his most powerful form.

Square Enix

 * Final Fantasy
 * Kefka Palazzo: The entire game of Final Fantasy VI follows Kefka slowly but surely sliding even deeper into complete madness than he already is.
 * Professor Hojo: By the time the party faces him, he's completely lost what sanity he ever had and raves that he's an idiot for not realizing the full potential of his experiments and writing them off.
 * Kadaj: Lets out an anguished wail and then quiets into sobs when he sees the "mother" he's been pursuing is a puddle goo. After Cloud arrives, he attacks him furiously.
 * Ultimecia: She has two; first, when the SeeDs team finally meets her in person, she flies into a rage about how they are always getting in the way. Then, once she was forced into her final form, she flatly states her new goal in destroying everything within the universe.
 * Kuja: When he finds out that he has a limited lifespan he stops pretending to be sophisticated and composed and just grabs power and wrecks stuff.
 * Caius Ballad:
 * Bhunivelze: He initially allows Lightning to fight him prove her worth to him so he knows she is ready to become the Goddess of Death. As it becomes apparent that she is not only trying to kill him, but may be capable of doing it, he becomes increasingly enraged, and when he enters his 4th form he screams at her. After the fight, he becomes completely unhinged to the point of snarling and growling at her.
 * Ardyn Izunia: He experience this towards the end of the fight. Struggling to even swing his sword at Noctis, Ardyn drops all pretences of arrogance and pride and just rants angrily at him.
 * Kingdom Hearts
 * Ansem the Seeker of Darkness/False Ansem/Xehanort: Gets a rather subdued one in Kingdom Hearts: Dream Drop Distance when Riku rejects his offer to embrace the darkness.
 * Terra-Xehanort: He loses his cool in Kingdom Hearts: Birth by Sleep is when the Lingering Will form, prompting a snarl of disbelief. In the subsequent battle he begins by walking towards it slowly, taking the time to block and counter it attacks and attacking back carefully. As the battles continues he starts teleporting rapidly, attacks more aggressively, and breaks out meteor as his desperation attack.
 * Xigbar: Experiences two brief ones in 3D when Sora states that even though he is not one of the Keyblade chosen ones, he's proud to be connected to the people that are and also when Lea shows up to save Sora from becoming one of Master Xehanort's vessels. In the former, he drops his affable demeanor and reasserts in a stunned tone that those are just words and Sora has lost. For the Latter, he finally starts showing real anger and tells Master Xehanort "What now, you old coot?!".
 * Zexion: He loses it when Riku embraces the darkness and stands against him.
 * Larxene: Once she realizes her and Marluxia's plan crumble due to Axel's actions, she exposes everything to Sora, and goes ahead to eliminate him with "no other choice" left, leaving her vulnerable to do something stupid, and in turn, meeting her demise.

Sega

 * Sonic the Hedgehog
 * Metal Sonic: Reach this point when Team Sonic defeated him in Sonic Heroes.
 * Dr. Eggman Nega: At the end of Sonic Rush Adventure, he activates the Egg Wizard's Planet Buster Laser in a final attempt to defeat Sonic and Blaze, much to Eggman's dismay.
 * Erazor Djinn: When Sonic reseals him back into his lamp.
 * Infinite: He has a huge one after Shadow humiliated him, going into a insane freak-out which pushes him into becoming Eggman's powerful weapon.
 * Puyo Puyo
 * Doppelganger Arle: Once she is defeated, she freaks out over being unable to beat Arle, screaming that she is the real Arle before fading into nothing.
 * Satan: Starts completely crying when his for head of hair.
 * Shin Megami Tensei
 * Persona 3: Takaya Sakaki: In the movie, Takaya begins to lose his shit after SEES awakens their Ultimate Personas and Jin's death.
 * Persona 4
 * Shadow Yukiko: She went into dismay and wastes a turn when her Prince refuses to heed her summons.
 * Mitsuo Kudo: He falls into insanity after his confession is ignored and refusing to accept his own Shadow, causing it to be.
 * Tohru Adachi: When confronted at the end by the team, he start acting like a child throwing a tantrum.
 * Persona 5
 * Suguru Kamoshida: The real-life counterpart of Kamoshida was visibly enraged when he saw calling cards of the Phantom Thieves all over the board, angrily questioning other students and ranting until he spot Ryuji, the Protagonist and Ann. Kamoshida threatened them as they would be expelled, as Shadow Kamoshida surfaced and threatened the Thieves. Asmodeus has one over the course of his boss fight as the party takes away his trophies, being shocked into dropping his guard after his trophy cup is destroyed, and have fall into despair after his crown is taken. By the end of it, he doesn't even care if he lives or not.
 * Ichiryusai Madarame: After being defeated, Shadow Madarame was reduced into a terrified man who pleadged for mercy and begged Yuusuke to stay beside him, but Yuusuke only wanted him to repent for his crimes. Back in the real world, after having his heart stolen, the real-world counterpart of Madarame made a conference and confessed his crimes, even to the point of crying desperately onscreen.
 * Junya Kaneshiro: When the calling card arrives, he threatens his men to hand over everything they've earned at once lest he kill them while he and his mistress intend to skip town.
 * In the animation series adaptation, Shadow Kaneshiro visibly lost his composure when Ann summoned Carmen and burned down his cash, resulting in Thieves attacking his Piggytron and blowing it up, defeating him.
 * Cognitive Wakaba Isshiki: Cognitive Wakaba was visibly enraged when Futaba awakened her Persona, Necronomicon, and helped the other Thieves to attack her.
 * This is amplified in the animated series. While being shot down, Cognitive Wakaba started to rant to Futaba as her face started to twist and turned beastly, yelling that she should never give birth to Futaba, but Futaba refused to listen and allowed the Protagonist to give the monster a final blow.
 * Kunikazu Okumura: Sort of. Unlike other major targets of the Thieves, neither Okumura himself nor his Shadow ever lost composure at the beginning, either on the arrival of Calling Card or the boss battle. However, it didn't last long. After losing all of his staff members, Shadow Okumura was shocked and tried to summon more robots to fight for him. Much to his disappointment, no one ever came. Shadow Okumura then went into a catatonic state as the Thieves landed attack upon him, defeating him.
 * In the animated series, this was displayed much further after Shadow Okumura's defeat. As the Thieves escaped his Palace, Shadow Okumura broke down crying and promised to make Haru happy once more. However, his remorseful atonement was cut short when the Traitor ambushed and killed him.
 * Sae Niijima: Before the boss fight in Casino Palace, Shadow Sae claimed she would fight fair and square with the Phantom Thieves. However, it was revealed that she actually cheated during the roulette phase. After the Thieves blown her hypocrisy, Shadow Sae felt humilated and transformed into her demon form, roaring that she would crush the Thieves "fair and square as [The Thieves] like".
 * The Traitor: During the first phase of confrontation against the Traitor, his mentality went more and more unhinged and filled with hateful rage. Then, at the beginning of his second phase, he ranted at the Protagonist for having everything he don't and showed disregard towards the power of friendship, before revealing himself to be the Black Mask, the same executioner in the mental shutdown events. Then, the Traitor claimed he would show the Thieves his true power and kill them all so that he would prove he's better than them. Then, by summonning his Ultimate Persona, Loki, the Traitor induced the psychotic breakdown on himself and went psychotic as a result. Soon, the Traitor laughed like a sick psychopath and attacked the Theives mindlessly, claiming that they would die together. In the end, the Traitor calmed down and admit defeat after the end of his second boss fight.
 * Masayoshi Shido: After the Thieves made a nation-wide broadcast to expose him, Shido was enraged and desperately made his minions to find a way to stop the Thieves to steal his heart, before ordering them to find the Traitor for failing to take the Thieves down. After his Shadow was defeated, Shido felt his heart being stolen and tried to eat a special pill, causing him to lose conciousness temporarily so that his Palace would be destroyed, taking the Thieves with him. This eventually failed and the Theives left unscathed with Shido's Treasure. Days later, after he was elected as Japan's Prime Minister, Shido started to confess his crimes during his speech as a result of his heart being stolen, before he collapsed and lost his conciousness.
 * The Conductor: During the final boss battle, the Conductor was surprised when he witnessed humanity stood up against him and support the Phantom Theives, but still kept sumg. Then, the Protagonist summoned his Ultimate Persona, Satanel, with Arsene reborn and broke his chain. Then, the Conductor was shocked to see Satanel, before the Phantom Thieves was cured of their injury. Believing the humanity is destinied to doom because of their foolishness, the Conductor turned noticibly enraged and horrified. He tried to eliminate the Phantom Thieves, only becoming shocked to find his attack futile towards all of them. Then, with the power from humanity's support, the Protagonist used Satanel's power and shot the Conductor in the head to kill him. Before being shot to death, the Malevolent God ranted that the Theives were trying to rob people's wishes.

World of Warcraft

 * Perhaps the most disturbing Breakdown in WoW is Deathwing's Breakdown. After his apparent defeat when falling into maelstorm and having his body armor destroyed, Deathwing was yet to be destroyed. He soon emerged from the maelstorm as an utterly deformed and insane abonomation known as "Madness of Deathwing". Most of his body (except his head) are barely recognizable and remained just exploding lava blood. He began to attack his enemies in blind fury and tried to summon the second Cataclysm to take Azeroth down. At this time, everything connected to the once-good Neltharion the Earth-Warder had all gone forever. All it remained outside Deathwing is just deformation, and all it remained inside him is just insanity.

Injustice

 * Superman: Gets overcome with paranoia and determines that the world is ungrateful for his "protection", even deciding to set an example by destroying both Metropolis and Gotham City before he would invade the Justice League's universe, thus showing his true colors.
 * Brainiac: Becomes angry when Superman controls his ship to restore the cities Brainiac stole and takes it out on Batman by attacking him. He already has a Breakdown prior to that, when he is preparing to fight Superman, taunting the Kryptonian that he had killed billions of Superman's race in the process of destroying Krypton before their battle starts.

Sony

 * God of War
 * Greek Era
 * Zeus: By the end of the final battle, Zeus is left screaming at Kratos. And as Kratos charges at him to bash his face in repeatedly, he show a look of Fear on his face for the first time, revealing the evil that had infected him.
 * Athena: When Kratos kills himself and foils her plans, she throw a brief tantrum before coldly remarking that Kratos had disappointed her and leaving him to die.
 * Lahkesis: She goes from cool and arrogant upon meeting Kratos to increasingly more nervous during their boss fight and outright goes into an unpleasant development when he traps Atropos in the past.
 * Norse Era
 * Baldur: He fully believes he's kill Kratos and Atreus in their final fight with him, and even thanks them for removing immortality. When Kratos activates his Spartan Rage and turn the tables on him, its suddenly dawns on Baldur that he could actually lose after have nothing new to throw at them, reducing him to screaiming at the two of them.
 * Magni and Modi: The death of Magni has had a devastating effect on Modi. In a fit of grief he makes a surprise attacks on Kratos and Atreus. Rather than kill Kratos on the spot, he kept blabbering about how he wouldn't be able to rightfully earn Thor's hammer and how he plans to kidnaps Atreus to replace Magni. When Kratos sends him away, Modi is on the verge of tears. When Modi is met the final time he dies defiantly by insulting Faye, at this point Modi doesn't care anymore.
 * Uncharted
 * Zoran Lazarevic: More than often, but when he drink the sap in the late of the game, he went into a berserker rage.
 * Harry Flynn: Possibly, his attempt to kill the heroes; when it's not Drake who mortally wounds him but Lazarevic. Needing to be rescued by the people he turned against was also not good for his ego.
 * Talbot: He flips out when Marlowe is killed, and concentrates solely on killing Nate, rather than escaping the rapidly collapsing Ubar.
 * Rafe Adler: Throughout A Thief's End he shows signs of being a rather sociopathic and unhinged person, beginning with his murder of the prison guard for asking a larger cut for Avery's treasure. However, his meltdown is in a full swing once Nadine locks him and the Drake brothers in Avery's ship. Instead of trying to find a way out, he forces Nathan into a duel to the death, even though Nate doesn't even care about the treasure anymore and just wants to leave the ship alive with his brother.
 * Ratchet & Clank
 * Dr. Nefarious (original): He gets quite a few of them, especially in A Crack in Time where Ratchet's time-travelling damages his circuity. Also, he's prone to randomly shorting out and playing soap operas if he gets too hammy with his breakdowns.
 * Dr. Nefarious (remake): After Ratchet sabotages the Deplanetizer, Dr. Nefarious loses his mind and initiates a backup plan--detonate a dwarf star that powered the weapon, which would destroy the planet Umbris and everything else around it.
 * Courtney Gears: She snaps after her favorite dancer is killed.
 * Sly Cooper
 * Rajan:
 * When the Cooper Gang floods his temple hideout, he comes charging out and starts chewing the scenery, hamming it up with such terms as " Black Clouds and Thunderbolts", Clockwerk's Black Heart," and starts an arrogant boast.
 * Even before this, his embarrassing loss of the Clockwerk Wings, Carmelita's immediate arrest of several guests at his Ball, and being forced to flee his own palace completely breaks his composure.
 * Neyla: After her plane is shot down in Canada, and after being wounded as Clock-La by Carmelita and Sly. During the final portion of the Clock-La fight, she's pretty much snapped, screaming that she'll hunt Sly down and kill him in his sleep.
 * Dr. M: In the ending of Sly 3, with the whole vault coming down, Dr. M starts screaming and pounding his chest, refusing to leave as it collapses. Before that, when Sly insists he's his own person, and not just the latest in the Cooper line, Dr. M refuses to accept it, proclaiming him to be nothing more than an grabbing-attention thief.
 * Sheriff Toothpick: His PA messages during the final mission of the second episode slowly get more and more crazy. By the time Sly reach him, he's pretty much snapped.
 * Ape Escape: Specter: In the first game, after noticing Spike's power and strength, he becomes hellbent on bringing him over to his side, eventually resorting to brainwash and torture when his many persuasions fail. When Spike resists and overpowers him, Specter panics and tries to outright destroy him before finally being driven into exile.
 * Killzone: Jorhan Stahl: Has one after it's revealed that the Helghan Senate has declared Orluck Autarch instead of him, and intends to force him to hand over all of his weapons to the military or face being declared an enemy of the state, and this comes hot on the heels of his intended gambit to rule Helghan being in ruined when Sev and Rico breaks the ISA prisoners out of his weapons facility on a national broadcast.
 * inFamous: Joseph Bertrand III: During one of Wolf's dead drops, Bertrand has a full-blown temper-tantrum when he discovers the nature of his powers, complete with furious accusations, death threats, anguished pleas to God, broken glass, and a loud and angry shout.
 * Gravity Rush: Cai: He throws a temper tantrum after Kat defeats Elektricitite, going into a motive rant explaining why the weak should die.
 * The Last of Us
 * David: He gets more and more unhinged the longer Ellie interacts with him. By the end, he's a complete lunatic.
 * James: He loses his cool when Ellie bites David, which gives her the opening to shanks him to death and flee.

BlazBlue

 * Yuuki Terumi: Happens three times over the course of Chronophantasma.
 * Hazama: His temper gets disintegrates when his fun is interrupted or his plans go awry beyond recovery in an iteration.

Others

 * Lord Brevon: As Lilac, Carol, and Milla get closer and closer to defeating him and saving Avalice, he becomes more and more obsessed with killing them above all else. His initial tactics with them after they board his spaceship include opening the airlocks, shutting off the oxygen supply for his ship, forcing his own loyal servant Serpentine into a painful transformation to better fight them, and opening fire on them with turrets that follow them. By the time the heroines enter the last phase of the final battle, he has snapped completely, quickly rushing around the area while snarling crazed threats. In Milla's story, after Milla has destroyed his mech armor, he angrily tries to strangle her only for Lilac to come to her rescue by attacking him and then severely beating him up while shouting at him not to hurt Milla.
 * Skull Face: Upon sees that the treacherous Psycho Mantis prematurely activates Metal Gear Sahelanthropus by channeled it with certain individual's hatred (who is stationed inside a Diamond Dogs helicopter), Skull Face was so horrified that he demanded who had more of a lust for revenge than even he and forced his men to took him away for safety due to his shock and confusion.
 * Skull Face also revealed to have another breakdown previously as revealed in one his of cassette tapes. He loses his cool when Code Talker figures out why Skull Face is so hell-bent on finding out how to stop the symptoms of the vocal cord parasites from manifesting. The reason for this is because in attempting to create more strains of the vocal cord parasite, Skull Face became infected by the strain that responds to his own mother tongue: the Hungarian strain that responds to the Szekelys dialect.
 * Moustache Girl: After she finds out that Hat Kid does not want to help her beat up the bad guys, Moustache Girl turns traitor and angrily voices her plan to get rid of all the bad guys. She gets into another villainous breakdown when Hat Kid tries to reconcile with her near the end, leading to an inevitable final battle with Moustache Girl's psyche and soul so gone that she is unreasonable and transforms into an almost pure evil being.

Internet

 * Perhaps the most BRUTAL AND VIOLENT BREAKDOWN EVER suffered by the whole citizens of Backwater Gospel town. Cause of this was due to the Undertaker comes to the town with intention to claimed one of their lives. When the citizens of the Backwater Gospel town realized that the Tramp, the crippled man that they murdered was not the very life that he sought, one of them snapped, and sliced a short-haired girl's head into 2 with an axe, triggering the gory and violent massacre where everyone brutally killed each other with the highly gruesome ways.
 * The Nostalgia Critic is have some an lot of breakdowns by reviewing all poorly rating films here are some of his breakdowns:
 * In the review of The NeverEnding Story 3 that he was getting angry when the Rock Biter is been changed him to kindful to lazy and even the music that he was going insane, but in the ending credits of the film he would like to heard the classic music but it use the Rock Biter music then Nostalgia Critic walks off, drives off to the workshop to buy the hammer, then smashes the DVD of the movie going insane to destroying it.
 * The famous breakdown of him is the begining of the review of FoodFight! that he was watch this that he was shocked that he wreck the DVD and even the food's with the frying pan (which it was an parody of Catwoman from Batman Returns) that he warns the people of this film.
 * In the review of Battlefield Earth, he has a complete meltdown over the movie's sheer stupidity and runs around his room screaming random obscenities as the camera speeds up for comedic effect.
 * Russell Barnes: After his plan to swap bodies with a sorcerer was thwarted several times, he initiates Black Protocol on the servers of the game, Age of Adventurers, in an attempt to kill off the players trapped inside to cover up his crimes.

RWBY

 * Salem: When Hazel reveals that Ozpin is still alive, Salem's rage becomes so great that the windows begin to crack and she harshly orders her subordinates to leave before letting out a primal scream of fury that shatters the room's windows.
 * Cinder Fall: Loses it when Jaune Arc (somewhat clumsily) nearly manages to kill her while she was stunned by the activation of Ruby Rose's Silver Powers power and stomps on top of him while angrily asking him if he really had a chance of defeating her and calling him a failure with a death wish.
 * Emerald Sustrai: Upon seeing Yang return with the Relic with no sign of Cinder, Emerald bursts into tears at the thought of Cinder being gone. When pressed by Mercury by escape, Emerald screams to create one mass illusion that leaves her unconscious while Hazel carries her to safety.
 * Roman Torchwick: After Ruby forces Neo off the ship, she declares that she would never give up her fighting spirit no matter what he throws at her. Roman's fighting style become much more aggressive; he drops the cute one-liners and back-talk and concentrates on a swift execution of moves that overpowers Ruby and forces her to the ground. As she falters, he begins ranting at her and beating her over and over with his cane. So furious with her determination to be a hero that he doesn't spot the huge Griffon that lands directly behind him.
 * Tyrian Callows: When Salem tells him that she is disappointed by his failure to capture Ruby, Tyrian collapses sobbing helplessly. A Beowulf tries to ambush him, thinking him easy prey, but Tyrian pushes out at the creature and sends it flying. He then leaps onto the fall Grimm and begins slashing at it over and over again while it struggles in vain to escape. As Tyrian slashes, his sobs begins to turn to maniacal laughter until he is crying and laughing at the same time. He doesn't stop even when the Grimm begins dissolving away into nothing. His breakdown is witnessed by Cinder, who watches it unfold in speechless horror.
 * Corsac &amp; Fennec Albain: After their assassination attempt on the Belladonnas fails and ends in his brother's death, Corsac's calm demeanor goes out the window as he struggles to his feet and screams at the Belladonnas and Sun.
 * Ilia Amitola: During her fight with Blake, she starts to breakdown when she confronted with the choices she has made, as well as Blake's continuous faith that she is a good person deep down. Ghira almost sacrificing himself to save her as well as knocking out Corsac leads her to finally break down crying in front of the family.
 * Raven Branwen: When Yang confronts Raven outside the Spring Maiden's vault, Raven tries to justify why she was part of the attack on her daughter and brother's group, and makes fun of Yang for believing what Ozpin has said. She dismisses Raven's attempts to justify her beliefs and brutally shut down Raven's perception of strength and mercy, causing Raven to blow her top. As Yang out Raven as a coward who hides her weaknesses behind a façade of power, concluding that she'll confronts her fears while Raven runs from them, a distraught Raven is moved to tears; she gives into Yang's demands with a whimper, hands over Relic of Knowledge and flee out of regrets, leaving her daughter to face the threat of Salem in her tead.

Red vs. Blue

 * Alden Price: When he realizes that the Chrous armies are likely to win, he tries to escape with the Tartarus. When questioned on this decision, he shoots one of his own men, then raises his voice for the first and only time in the series.