Have you any idea how much tyrants fear the people they oppress? All of them realize that, one day, among their many victims, there is sure to be one who rises against them and strikes back!
~ Albus Dumbledore's statement on Harry Potter regarding the fact that by destroying the innocence of those whom survived his antagonism, Lord Voldemort has created many enemies, includes Harry himself.
Destroying the Innocent is an event where a villain destroys another character's "innocence." These villains are known as Destroyers of Innocence. A villain becomes a "Destroyer of Innocence" when they harm, injure or even kill a friendly, defenseless or an innocent character. Destroying the Innocent is event that invokes great feelings of anger and hatred by the public and marks a crossing at Moral Event Horizon. Like Moral Event Horizon, acts of destroying the innocence can also insult/disgusted other villain that witness this event as well.
A destroyer of innocence often do not have qualities of redemption due to the fact that they are not above destroying innocence of some innocent person. Some villains who created this kind of catastrophic event in their own universe are often Complete Monsters, but not all of them are necessarily Complete Monsters, unless if they have reached a new heinous standard in their universe. On the other hand, a certain destroyer of innocence's actions are proved not only limited with invokes great feelings of anger and hatred by the public alone, but also invokes immense fear in public's heart(especially if the said action vile enough to the point that mentioning their name or even discussing about them considered as taboo or they later became damned souls as comeuppance/price of their actions). Quite often, those who have their innocence destroyed may turn evil themselves, kill the villain in revenge, or worse, became their subordinate.
Most importantly, destroyed a character's innocence- they wouldn't be a Destroyer of Innocence otherwise. This means, acts where villains destroy their own innocence instead of the heroes' are not to be counted as one- that goes under Moral Event Horizon.
Here are lists of notable villains that have destroyed innocence:
Anime and Manga
Hotshot TV Producer: He tried to sexually entice Miku, however, Miku refused to accept the situation and left the place and never spoke to the Producer again. After that, the Producer spread false news about Miku, the news was so outrageous that all fans of Miku were leaving her one by one. And in a final attack, he made Miku contracting a disease that made her lose her voice, as well as also lost her singing career. The case Miku was so horrible, which made Miku thoughts of suicide after she lost everything. The Producer is also the responsible for making her have hatred of men, and he often regarded as one of the worst villains in Date A Live.
Phantom: When she gave Spirits' powers to Kotori Itsuka and made her burn down a part of Tengu City and so also was responsible for make Origami kill her own parents.
General White: Threatened to kill the Village Elder and almost killed Goku. This resulted in provoking #8 who killed him.
Van Zant from Dragon Ball Z: Killed several innocent people and almost killed Mr. Satan and Bee, this resulted in Evil Buu's birth and their own death. This action later revealed turned him into a damned souls as when Earth restored and all lifeforms inside it revived, he remained dead.
Tomoo and his gang from Elfen Lied: Destroying Lucy's innocence, they bullied Lucy for fun & brutally killing her pet puppy on purpose by forcing her to watch without any remorse. They are also responsible for turning Lucy into a murderous psychopath. They are a famous example of a "destroyer of innocence".
Kureo Mado from Tokyo Ghoul: He had brutally killed and murdered countless ghouls all to get revenge for the one who killed his wife. He had killed Asaki and Ryouko Fueguchi and used their kagunes as weapons. He also tried to kill their daughter Hinami and he used the Quinque that was made form her mother's kagune and almost killed both Hinami and Touka.
Like Mado himself,C.C.G, the very organization that Mado affiliated with, though duty was for keeping ghouls from harming humans, proved to being too genocidal in nature as their action was mainly involving killing-spree against all ghouls in existence until none of them left. Worse, they did so without seeing their morality and in process, destroyed innocence of many ghouls that turned out not evil. This includes Ayato Kirishima's, whom joined Aogiri Tree to wage war against them.
Mado's act of destroying the innocence above was said reasonable due to his innocence brutally destroyed by One-Eyed Owl via brutally mangled Mado's wife
Yakumo Oomori from Tokyo Ghoul: Yamori was infamous for his brutality and had killed countless innocent civilians before. He had terrorized the Fueguchi family and almost killed Asaki and had kidnapped Ken Kaneki and tortured him for ten days. He had turned Kaneki into a complete ghoul and it led to his downfall. While this act negative enough to considered as Destroying the Innocent, Kaneki's change after the said torture has made him more ruthless in his resolve to protect the others which somewhat beneficial due to prior of being tortured, his resolve was not strong enough for him to use his ghoul powers to protect the others.
Aya Tokoyogi: Destroyed her own daughter's innocence right before killing her.
Yami Marik: He destroyed Marik's innocence when he took Marik over for the first time when he was a child and murdered Marik's father (sent him to the Shadow Realm in the 4Kids dub.)
Madara Uchiha: Destroyed Obito Uchiha's innocence by arranging Rin's death, turned him into executor of his evil plan for years until his resurrection.
Wild Hunt (Akame Ga Kill!): This organization's true purpose was in reality, purges many innocent lives as much as they can as means to satisfy Honest's sadistic hunger for humanity's pain which ruined the innocence of those whom survived their killing spree.
Champ (Akame Ga Kill!): Champ as brutally destroyed many children's innocence by raping them before butchering them like a cattle.
Itachi Uchiha: Destroyed his younger brother's innocence by forcing him to watch how he killed the whole Uchiha Clan via tsukuyomi. Though later revealed that Itachi only did so to encourage Sasuke to killed him in order to keep Uchiha Clan's name from ruined as the said clan planned to usurp Konoha, damage that he has done on Sasuke's innocence was too great to the point that Sasuke turned to the dark side and became a figure that Itachi doesn't want him to became.
Joker (DC Animated Universe): Brainwashed Tim Drake (whom taking Robin mantle at the moment) into Joker Junior. Worse, in events of Batman Beyond, it was revealed that he has uses Tim Drake as his vessel for his soul (or specifically his consciousness) via chip that contains his memory within Tim's head, turned him into another Joker.
Eddy (Ed, Edd, n Eddy): Eddy destroyed Jimmy's innocence in the episode "Ed in a Halfshell" (though in a less serious way) when he taught Jimmy "everything he knows"; before the episode, Jimmy was, for the most part, harmless, but after that episode, Jimmy becomes a conniving schemer (this is most prevalent in the two-part episode "If It Smells like an Ed", where he orchestrates a very elaborate plan for revenge by framing the Eds for things they didn't do as revenge after Eddy gave him a wedgie in front of the entire Cul-de-Sac.)
Shredder (2012 TMNT): Shredder destroyed Hamato Yoshi's innocence killing (by accident) Tang Shen and took his daughter Miwa.
Emperor Palpatine from Star Wars: Seduced Anakin into the Dark Side with the promise of keeping Padme safe, and ultimately transformed him into Darth Vader.
Koba from Dawn of the Planet of the Apes: Devastates his own kind's innocence by set their own colony ablaze and framing the humans for it.
Judge Hopkins from Paranorman: He and other judges having Aggie Prenderghast, executed via hanged out of fear with her unusual powers despite the fact that she never harmed anyone, thus turning Aggie into a vengeful wraith bent on revenge.
Clarence Darby: Raped and murdered Clyde Shelton's wife and daughter and caused Shelton to become a deadly vigilant by killing a majority of the Justice Department in Philadelphia and even brutally killing Darby himself.
Eli Damaskinos: Has destroyed his own son's innocence by turned him into Alpha Reaper out of his ambition for vampirekind's ascension, and also arrogantly mocked his own daughter for berating him.
Laserbeak, from the Transformers: Dark of the Moon, he killed possibly hundreds of innocent people, before and after the Chicago battle, and he possibly killed a whole family of a NASA engineer when Laserbeak tricked his daughter into letting him inside. Laserbeak takes sadistic pleasure from destroying innocents.
Sentinel Prime and Dylan Gould from: Aside inevitably/posthumously caused mankind and Autobots enemies via their actions in devastating Chicago and kills many people in the said city, both has posthumously destroyed James Savoy's innocence, turned him into a vengeful member of Cemetery Wind that hellbent in destruction of all Cybertronian on Earth.
This is the entire purpose of The Rogue Isles in City of Villains. Lord Recluse has set up a trial by fire, eat or be eaten, style of society there with the grand goal of manufacturing villains from ordinary or even previously good-hearted people.
In City of Heroes/VillainsGoing Rogue the society of Praetoira was introduced and with it Mother Mayhem. Mother uses her Seer Network to detect blossoming psychics, abducts them, sticks them in isolation, telepathically torture them until their old lives and values are meaningless to them before finally psychically enslaving them to her will.
Ganondorf destroys Link's innocence countless times in all his incarnations, most notably in The Wind Waker, where Link is living peaceably on Outset Island and then his sister is kidnapped by the Helmaroc King working for Ganondorf, and then in Twilight Princess when Ganondorf orders Colin, Beth and other children kidnapped, and Link is suddenly thrown into a dark world of political conflict.
Joker (Video Games) from Injustice: Gods Among Us: Destroyed Superman's innocence and turned him to the side of evil by manipulating him to kill Lois Lane and his unborn child, activating a bomb to destroy Metropolis with the detonator in Lois' heart to activate once her heart stops beating.
Yuuki Terumi from BlazBlue: Destroyed Ragna innocence by kidnapping his sister when they were children.
The Killer destroyed the innocence of the five children he murdered, turning them into ghosts who would kill any security guard they came across and eventually led the Killer to his own gruesome demise.
Alex Mercer inevitably destroyed James Heller's innocent side when he causes death of Heller's family when he caused the second outbreak in New York.
Lucifer (Dante's Inferno): He destroyed Beatrice's innocence when he convinces her to eat the Forbidden Fruit, turning her into a succubus. The purpose of this act was believed to be turned her against Dante, but when Dante undo this by cleanse her soul and later confront Lucifer in Cocytus, it's revealed that Lucifer's true goal in doing so was to challenge Dante further as well as free himself from his prison.
Ridley from Metroid: Destroyed Samus Aran's innocence during his invasion in planet K-2L by killing her mother as well as the rest of humans on the said planet when she was 3, presumably leaving her as sole survivor.
Ozwell E. Spencer: Sadistically ruined Lisa Trevor's innocence by turned her into a monster that gave birth to G-Virus inside her and killed her parents just as means to prevent his research to be a God.
Joe Chill from the Batman comics and media: Murdering Bruce Wayne's parents.
Dennis Carradine: Murdered Peter Parker's Uncle Ben, kickstarting his becoming into Spiderman.
Live-action TV & TV Shows
Madame Kovarian: She destroyed the innocence of Melody Pond (AKA River Song) when she conditioned her from the time she was an infant to become a psychopathic assassin with the sole purpose to kill the Doctor. By extension, it can be considered that she destroyed Amy's innocence too when she kidnapped and experimented on her at Demon's Run.
Ra's al Ghul (Arrow): He destroyed Oliver Queen's innocence when he brainwashed him into becoming Al Sah Him in exchange for his sister's resurrection.
Tywin Lannister: He destroyed the innocence of all three of his children due to the years of psychological abuse he inflicted on them, thus making him directly responsible for making all three of them who they are (Jaime and Cersei specifically.) By extension, this also makes him responsible for making his grandson, Baratheon Joffrey, who he is too.
Azazel: He destroyed Sam Winchester's innocence (as well as the innocence of the other special children, and by extension, he destroyed Dean's innocence as well) when he injected Sam with demon blood when he was a baby, thus resulting in his special powers (and setting in motion much of the plot of Seasons 1 & 2.)
Lord Voldemort: He has started committing various acts of destroying the innocence even from his own childhood that ultimately made his name became the greatest taboo within Harry Potter series. Even Dumbledore not only pointed out that by doing so (includes creating Horcruxes), Voldemort has gone beyond usual evil and caused many people stand up against him even from his own followers.
Bellatrix Lestrange: Has gleefully tortured Neville's parents into insanity, traumatizing him in process.
Yeerks: The faction of this race has infamously ruined countless lives' innocence during their campaign in world domination. Though being defeated by Animorphs and also Andalite forces, this was not without the enormous losses, includes deaths of Tom and Rachel which ruined Tobias and Jake's innocence.
(Manny: Alright, let them go!) I don't think so. You destroyed everything I had! I'm just returning the favor.
~ Captain Gutt holding Manny's family hostage, stating that the mammoth took everything he had from him, and the evil captain intended to do the same.
Children...Ah! Killing them is actually a great favor to mankind and for each person on the face of this planet, especially when those damn "cute little fucking faces" give false hopes to the humanity. I love to kill them, they are more attractive dead. I'm not the "villain" here, I'm just ridding the world of these pests. I'm sure that "monster" also think the same.
What's the matter, Batman? No witty comeback? No threat? Then I'll provide the narration... I'll begin with how I peeled back the layers of the boy's mind. Oh, he bravely tried to fight it at first. You would've been proud to see him so strong. But all too soon, the shocks and the serums took their toll, and the dear lad began to share such secrets with me. Secrets that are mine alone to know... Bruce. It's true, Batsy! I know everything. And kinda like the kid who peeks at his Christmas presents, I must admit, it's sadly anti-climactic. Behind all the sturm and bat-o-rangs, you're just a little boy in a playsuit, crying for mommy and daddy! It'd be funny if it weren't so pathetic. Oh, what the heck, I'll laugh anyway. HA HA HA HA HA HAA!
Had you not been so selfish, your little girlfriend's death would have been quick and painless, but now that you've really pissed me off, I'm gonna finish her, nice and slow. MJ and I; we're gonna have one hell of a time!
(Frollo locks the miller and his family in their own home with a spear. He turns to Phoebus.) Burn it. (Phoebus: What?!) Until it smoulders. These people are traitors and must be made examples of. (hands Phoebus a torch) (Phoebus: With all due respect, sir, I was NOT trained to murder the innocent!) But you WERE trained to follow orders! (Phoebus angrily douses his torch in a water barrel. Frollo snarls with rage!) Insolent Coward! (grabs another torch and touches the flame to the windmill. The entire structure is quickly engulfed in flame. Phoebus crashes through the window and brings the family outside to safety. Then Frollo's soldiers grab Phoebus) The sentence for insubordination is death, such a pity. You threw away a promising career. (Phoebus: Consider it my highest honor sir.)
~ Frollo ordering Phoebus to burn the innocent miller's house, but Phoebus refuses. When Frollo sets the house on fire anyway, Phoebus dives into the burning house and saves the family. In response, Frollo attempts to have Phoebus executed, but not before Esmeralda intervenes with a distraction.
Elia of Dorne. I killed her screaming whelp. Then I raped her. Then I smashed her fucking head in. Like this.
I believed we were doing what was right. I was wrong. Now this is our punishment. We thought we knew our way in life. But in death, we are lost. Please. Help us.
~ Judge Hopkins feeling remorse over his act that made Aggie ruin her own innocence
And to my son, The Stallion Who Will Mount the Word, I will also pledge a gift. I will give him the Iron Chair that his mother's father sat upon. I will give him Seven Kingdoms. I, Drogo, will do this. I will take my Khalasar west to where the world ends, and ride wooden horses across the black salt water as no Khal has done before! I will kill the men in iron suits and tear down their stone houses! I will rape their women, take their children as slaves, and bring their broken gods back to Vaes Dothrak! This, I vow, I, Drogo, son of Bharbo. I swear before the Mother of Mountains as the stars look down in witness! As the stars look down in witness! As the stars look down in witness!
I lost everything, I lost everything I loved. I lost my life, I lost my voice for that terrible man.
~ Miku Izayoi telling to Shido how she lost her innocence
Oh man. That sensation was better. I never had such a good experience as that day. So many beautiful and pure children .... I made love with all of them and then killed them so that they do not grow as dirty adults. AHH! I'd do it again, and again, and again. But the thing that annoyed me most that day was those damn brats were screaming: RUN-Sensei! RUN-Sensei! HELP US! This ruined my experience. I purged so many children that day that I even forgot about their faces.
~ Champ telling to Run how he raped and killed dozens of children.
Captain Gutt holding Peaches hostage, stating that Manny took everything he he had from him, and the evil captain intended to do the same.
Shen and his wolves attacking the innocent panda village.